Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MYPN
  • Mouse genes Mypn
  • Rat genes Mypn
  • Zfish genes mypn
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Mypn

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0008092	cytoskeletal protein binding	MYPN	IPI	UniProtKB:Q04020	Human	PMID:11309420
Molecular Function	GO:0051371	muscle alpha-actinin binding	MYPN	IPI	UniProtKB:P35609	Human	PMID:11309420
Molecular Function	GO:0051371	muscle alpha-actinin binding	MYPN	IPI	UniProtKB:Q08043	Human	PMID:11309420
Molecular Function	GO:0005515	protein binding	MYPN	IPI	UniProtKB:Q15327	Human	PMID:11309420
Molecular Function	GO:0005515	protein binding	MYPN	IPI	UniProtKB:P20929	Human	PMID:12482578
Molecular Function	GO:0017124	SH3 domain binding	MYPN	IPI	UniProtKB:O76041	Human	PMID:11309420
Cellular Component	GO:0005829	cytosol	MYPN	IDA		Human	GO_REF:0000052
Cellular Component	GO:0031674	I band	MYPN	IDA		Human	PMID:11309420
Cellular Component	GO:0031674	I band	Mypn	IDA		Mouse	MGI:MGI:5142381|PMID:11309420
Cellular Component	GO:0031674	I band	Mypn	IDA		Rat	PMID:11309420|RGD:8553772
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	MYPN	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	MYPN	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	Mypn	IDA		Rat	PMID:11309420|RGD:8553772
Cellular Component	GO:0030018	Z disc	MYPN	IDA		Human	PMID:11309420
Cellular Component	GO:0030018	Z disc	MYPN	IDA		Human	PMID:28017374
Cellular Component	GO:0030018	Z disc	Mypn	IDA		Mouse	MGI:MGI:5142381|PMID:11309420
Cellular Component	GO:0030018	Z disc	Mypn	IDA		Rat	PMID:11309420|RGD:8553772
Biological Process	GO:0045214	sarcomere organization	MYPN	IMP		Human	PMID:11309420

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern