Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MYO1C
  • Mouse genes Myo1c
  • Rat genes Myo1c
  • Zfish genes myo1ca,myo1cb
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Myo1c

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0051015	actin filament binding	Myo1c	IDA		Rat	PMID:15647165|RGD:11532774
Molecular Function	GO:0005516	calmodulin binding	Myo1c	IDA		Rat	PMID:18729383|RGD:11073624
Molecular Function	GO:0000146	microfilament motor activity	Myo1c	EXP		Mouse	MGI:MGI:3828899|PMID:19046570
Molecular Function	GO:0000146	microfilament motor activity	Myo1c	IDA		Rat	PMID:15647165|RGD:11532774
Molecular Function	GO:0000146	microfilament motor activity	Myo1c	IDA		Rat	PMID:20039646|RGD:11073623
Molecular Function	GO:0000146	microfilament motor activity	Myo1c	IDA		Rat	PMID:21680745|RGD:7349312
Molecular Function	GO:0005515	protein binding	MYO1C	IPI	UniProtKB:Q96J84	Human	PMID:21402783
Molecular Function	GO:0005515	protein binding	MYO1C	IPI	UniProtKB:Q9ULZ3	Human	PMID:24407287
Molecular Function	GO:0005515	protein binding	Myo1c	IPI	UniProtKB:Q9D945	Mouse	MGI:MGI:5796065|PMID:26961175
Molecular Function	GO:0005515	protein binding	Myo1c	IPI	PR:Q7TPH6	Mouse	PMID:15976448
Molecular Function	GO:0005102	signaling receptor binding	MYO1C	IPI	UniProtKB:O60500	Human	PMID:21402783
Molecular Function	GO:0031267	small GTPase binding	MYO1C	IPI	UniProtKB:P11233	Human	PMID:24056301
Cellular Component	GO:0009925	basal plasma membrane	MYO1C	IDA		Human	PMID:9858156
Cellular Component	GO:0005903	brush border	Myo1c	IDA		Mouse	MGI:MGI:5607232|PMID:20089841
Cellular Component	GO:0005903	brush border	Myo1c	IDA		Mouse	MGI:MGI:5621262|PMID:22114352
Cellular Component	GO:0005903	brush border	Myo1c	IDA		Mouse	PMID:15758024
Cellular Component	GO:0005737	cytoplasm	MYO1C	IDA		Human	PMID:21402783
Cellular Component	GO:0005737	cytoplasm	MYO1C	IDA		Human	PMID:9858156
Cellular Component	GO:0031410	cytoplasmic vesicle	Myo1c	IDA		Rat	PMID:22918957|RGD:11073622
Cellular Component	GO:0030659	cytoplasmic vesicle membrane	Myo1c	IDA		Mouse	PMID:12490950
Cellular Component	GO:0070062	extracellular exosome	MYO1C	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	MYO1C	HDA		Human	PMID:19199708
Cellular Component	GO:0070062	extracellular exosome	MYO1C	HDA		Human	PMID:20458337
Cellular Component	GO:0070062	extracellular exosome	MYO1C	HDA		Human	PMID:21362503
Cellular Component	GO:0070062	extracellular exosome	MYO1C	HDA		Human	PMID:23533145
Cellular Component	GO:0031941	filamentous actin	MYO1C	IDA		Human	PMID:9858156
Cellular Component	GO:0016328	lateral plasma membrane	MYO1C	IDA		Human	PMID:9858156
Cellular Component	GO:0016020	membrane	MYO1C	HDA		Human	PMID:19946888
Cellular Component	GO:0016020	membrane	MYO1C	IDA		Human	PMID:21402783
Cellular Component	GO:0045121	membrane raft	MYO1C	IDA		Human	PMID:23262137
Cellular Component	GO:0045121	membrane raft	Myo1c	IDA		Rat	PMID:21402783|RGD:8553556
Cellular Component	GO:0005902	microvillus	MYO1C	IDA		Human	PMID:9858156
Cellular Component	GO:0016604	nuclear body	MYO1C	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	Myo1c	IDA		Rat	PMID:15942958|RGD:1598733
Cellular Component	GO:0045335	phagocytic vesicle	Myo1c	IDA		Mouse	PMID:19144319
Cellular Component	GO:0005886	plasma membrane	MYO1C	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	MYO1C	IDA		Human	PMID:23262137
Cellular Component	GO:0005886	plasma membrane	Myo1c	IDA		Mouse	PMID:12490950
Cellular Component	GO:0032587	ruffle membrane	Myo1c	IDA		Rat	PMID:22918957|RGD:11073622
Cellular Component	GO:0032420	stereocilium	Myo1c	IDA		Mouse	PMID:17050716
Cellular Component	GO:0032421	stereocilium bundle	Myo1c	IDA		Rat	PMID:12486594|RGD:1298992
Biological Process	GO:0071346	cellular response to type II interferon	Myo1c	IDA		Mouse	PMID:19144319
Biological Process	GO:0032835	glomerulus development	myo1ca	IMP	ZFIN:ZDB-MRPHLNO-150819-3	Zfish	PMID:23715127
Biological Process	GO:0032835	glomerulus development	myo1ca	IMP	ZFIN:ZDB-MRPHLNO-150819-4	Zfish	PMID:23715127
Biological Process	GO:0032835	glomerulus development	myo1cb	IMP	ZFIN:ZDB-MRPHLNO-150804-2	Zfish	PMID:23715127
Biological Process	GO:0032835	glomerulus development	myo1cb	IMP	ZFIN:ZDB-MRPHLNO-150804-1	Zfish	PMID:23715127
Biological Process	GO:0030838	positive regulation of actin filament polymerization	Myo1c	IMP		Rat	PMID:22918957|RGD:11073622
Biological Process	GO:0030335	positive regulation of cell migration	MYO1C	IMP		Human	PMID:21402783
Biological Process	GO:0038089	positive regulation of cell migration by vascular endothelial growth factor signaling pathway	MYO1C	IMP		Human	PMID:23262137
Biological Process	GO:1900078	positive regulation of cellular response to insulin stimulus	Myo1c	IDA		Mouse	PMID:12490950
Biological Process	GO:1900078	positive regulation of cellular response to insulin stimulus	Myo1c	IMP		Mouse	PMID:12490950
Biological Process	GO:1900078	positive regulation of cellular response to insulin stimulus	Myo1c	IMP		Rat	PMID:22918957|RGD:11073622
Biological Process	GO:0090314	positive regulation of protein targeting to membrane	MYO1C	IMP		Human	PMID:23262137
Biological Process	GO:0090314	positive regulation of protein targeting to membrane	Myo1c	IMP		Mouse	PMID:12490950
Biological Process	GO:0090314	positive regulation of protein targeting to membrane	Myo1c	IDA		Mouse	PMID:12490950
Biological Process	GO:1900748	positive regulation of vascular endothelial growth factor signaling pathway	MYO1C	IMP		Human	PMID:23262137
Biological Process	GO:0006612	protein targeting to membrane	MYO1C	IDA		Human	PMID:21402783
Biological Process	GO:2000810	regulation of bicellular tight junction assembly	MYO1C	IMP		Human	PMID:21402783
Biological Process	GO:0030050	vesicle transport along actin filament	Myo1c	IDA		Mouse	PMID:12490950

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern