Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MYO16
  • Mouse genes Myo16
  • Rat genes Myo16
  • Zfish genes myo16
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Myo16

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003779	actin binding	Myo16	IDA		Rat	PMID:11588169|RGD:633234
Molecular Function	GO:0051015	actin filament binding	Myo16	IDA		Rat	PMID:11588169|RGD:633234
Molecular Function	GO:0005515	protein binding	MYO16	IPI	UniProtKB:Q8IZU9	Human	PMID:25902260
Molecular Function	GO:0005515	protein binding	Myo16	IPI	UniProtKB:P28660	Mouse	MGI:MGI:5304984|PMID:21946561
Molecular Function	GO:0005515	protein binding	Myo16	IPI	UniProtKB:O09008|UniProtKB:P28660|UniProtKB:Q6ZQ82|UniProtKB:Q7TMB8|UniProtKB:Q9R0X4	Mouse	MGI:MGI:5304984|PMID:21946561
Molecular Function	GO:0005515	protein binding	Myo16	IPI	UniProtKB:P62138	Rat	PMID:11588169|RGD:633234
Molecular Function	GO:0005515	protein binding	Myo16	IPI	UniProtKB:P63088	Rat	PMID:11588169|RGD:633234
Molecular Function	GO:0019903	protein phosphatase binding	Myo16	IPI	UniProtKB:P63088	Rat	PMID:11588169|RGD:633234
Molecular Function	GO:0044877	protein-containing complex binding	Myo16	IPI	RGD:3375|RGD:3377	Rat	PMID:11588169|RGD:633234
Cellular Component	GO:0005737	cytoplasm	Myo16	IDA		Rat	PMID:11588169|RGD:633234
Cellular Component	GO:0005829	cytosol	Myo16	IDA		Rat	PMID:11588169|RGD:633234
Cellular Component	GO:0016020	membrane	Myo16	IDA		Rat	PMID:11588169|RGD:633234
Cellular Component	GO:0016459	myosin complex	Myo16	IDA		Rat	PMID:11588169|RGD:633234
Cellular Component	GO:0005654	nucleoplasm	MYO16	IDA		Human	PMID:17029291
Cellular Component	GO:0005654	nucleoplasm	Myo16	IDA		Rat	PMID:17029291|RGD:8554212
Cellular Component	GO:0048471	perinuclear region of cytoplasm	MYO16	IDA		Human	PMID:17029291
Cellular Component	GO:0048471	perinuclear region of cytoplasm	Myo16	IDA		Rat	PMID:17029291|RGD:8554212
Cellular Component	GO:0005886	plasma membrane	Myo16	IDA		Rat	PMID:11588169|RGD:633234
Cellular Component	GO:0005886	plasma membrane	Myo16	IDA		Rat	PMID:17029291|RGD:8554212
Biological Process	GO:0021549	cerebellum development	Myo16	IEP		Rat	PMID:11588169|RGD:633234
Biological Process	GO:0008285	negative regulation of cell population proliferation	Myo16	IDA		Rat	PMID:17029291|RGD:8554212
Biological Process	GO:2000134	negative regulation of G1/S transition of mitotic cell cycle	Myo16	IDA		Rat	PMID:17029291|RGD:8554212
Biological Process	GO:0048812	neuron projection morphogenesis	Myo16	IDA		Mouse	MGI:MGI:5304984|PMID:21946561
Biological Process	GO:0014065	phosphatidylinositol 3-kinase signaling	Myo16	IDA		Mouse	MGI:MGI:5304984|PMID:21946561

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern