Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MYL11
  • Mouse genes Mylpf
  • Rat genes Myl11
  • Zfish genes mylpfa,mylpfb
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Mylpf

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	MYL11	IPI	UniProtKB:O43933	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	MYL11	IPI	UniProtKB:O76024	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	MYL11	IPI	UniProtKB:P14136	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	MYL11	IPI	UniProtKB:P28799	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	MYL11	IPI	UniProtKB:Q8WXH2	Human	PMID:32814053
Molecular Function	GO:0008307	structural constituent of muscle	Mylpf	IMP		Mouse	MGI:MGI:3773777|PMID:17356007
Cellular Component	GO:0005765	lysosomal membrane	MYL11	HDA		Human	PMID:17897319
Biological Process	GO:0033275	actin-myosin filament sliding	mylpfa	IMP		Zfish	PMID:32707087|ZFIN:ZDB-PUB-200728-9
Biological Process	GO:0006955	immune response	Myl11	IEP		Rat	PMID:16380169|RGD:1643015
Biological Process	GO:0006936	muscle contraction	MYL11	IMP		Human	PMID:32707087
Biological Process	GO:0060415	muscle tissue morphogenesis	mylpfa	IMP		Zfish	PMID:32707087|ZFIN:ZDB-PUB-200728-9
Biological Process	GO:0007519	skeletal muscle tissue development	Mylpf	IMP		Mouse	MGI:MGI:3773777|PMID:17356007
Biological Process	GO:0007519	skeletal muscle tissue development	Myl11	IEP		Rat	PMID:6179945|RGD:633441
Biological Process	GO:0007519	skeletal muscle tissue development	mylpfa	IMP	ZFIN:ZDB-GENO-211028-1	Zfish	PMID:32707087
Biological Process	GO:0007519	skeletal muscle tissue development	mylpfa	IMP	ZFIN:ZDB-GENO-211028-5	Zfish	PMID:32707087

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern