Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MYL12A,MYL12B
  • Mouse genes Myl12b
  • Rat genes Myl12b
  • Zfish genes myl12.1,myl12.2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Myl12b

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0032036	myosin heavy chain binding	Myl12b	IPI	PR:Q5SV80	Mouse	PMID:24825904
Molecular Function	GO:0005515	protein binding	MYL12B	IPI	UniProtKB:P35749	Human	PMID:19328794
Molecular Function	GO:0005515	protein binding	MYL12B	IPI	UniProtKB:P60709	Human	PMID:19328794
Molecular Function	GO:0005515	protein binding	MYL12B	IPI	UniProtKB:Q6X4W1-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MYL12A	IPI	UniProtKB:Q62868	Human	PMID:21457715
Cellular Component	GO:0045177	apical part of cell	Myl12b	IDA		Mouse	PMID:15037549
Cellular Component	GO:0005938	cell cortex	MYL12B	IDA		Human	PMID:23870127
Cellular Component	GO:0070062	extracellular exosome	MYL12B	HDA		Human	PMID:20458337
Cellular Component	GO:0070062	extracellular exosome	MYL12A	HDA		Human	PMID:20458337
Cellular Component	GO:0016460	myosin II complex	Myl12b	IDA		Mouse	PMID:21126233
Cellular Component	GO:0032991	protein-containing complex	Myl12b	IDA		Rat	PMID:15823548|RGD:1600561
Cellular Component	GO:0001725	stress fiber	Myl12b	IDA		Mouse	PMID:21126233
Cellular Component	GO:0030018	Z disc	Myl12b	IDA		Mouse	PMID:21126233
Biological Process	GO:0070527	platelet aggregation	MYL12A	HMP		Human	PMID:23382103
Biological Process	GO:0008360	regulation of cell shape	Myl12b	IMP		Mouse	PMID:21126233

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern