Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MYH8
  • Mouse genes Myh8
  • Rat genes Myh8
  • Zfish genes myha,myhb,myhc4,myhz1.1,myhz1.2,myhz1.3,myhz2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Myh8

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005524	ATP binding	MYH8	IMP		Human	PMID:17041932
Molecular Function	GO:0016887	ATP hydrolysis activity	MYH8	IMP		Human	PMID:17041932
Molecular Function	GO:0000146	microfilament motor activity	MYH8	IMP		Human	PMID:17041932
Molecular Function	GO:0005515	protein binding	Myh8	IPI	PR:P10126	Mouse	PMID:21689717
Cellular Component	GO:0005737	cytoplasm	MYH8	IDA		Human	PMID:21370490
Cellular Component	GO:0016459	myosin complex	Myh8	IDA		Mouse	PMID:1728586
Biological Process	GO:0046034	ATP metabolic process	MYH8	IMP		Human	PMID:17041932
Biological Process	GO:0048706	embryonic skeletal system development	myhz2	IMP	ZFIN:ZDB-GENO-180503-11	Zfish	PMID:28835471
Biological Process	GO:0030049	muscle filament sliding	MYH8	IMP		Human	PMID:17041932
Biological Process	GO:0014823	response to activity	myhz2	IDA		Zfish	PMID:16966387
Biological Process	GO:0003009	skeletal muscle contraction	MYH8	IMP		Human	PMID:17041932
Biological Process	GO:0048741	skeletal muscle fiber development	myhz2	IMP	ZFIN:ZDB-MRPHLNO-140619-4	Zfish	PMID:24523292
Biological Process	GO:0001501	skeletal system development	myhz2	IMP	ZFIN:ZDB-GENO-180503-11	Zfish	PMID:28835471
Biological Process	GO:0001757	somite specification	myhz1.1	IEP		Zfish	PMID:11002340

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern