Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MYBPC3
  • Mouse genes Mybpc3
  • Rat genes Mybpc3
  • Zfish genes mybpc3
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Mybpc3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042802	identical protein binding	MYBPC3	IPI	UniProtKB:Q14896	Human	PMID:18201573
Molecular Function	GO:0017022	myosin binding	MYBPC3	IDA		Human	PMID:10024460
Molecular Function	GO:0032036	myosin heavy chain binding	MYBPC3	IPI	UniProtKB:P12883	Human	PMID:17192269
Molecular Function	GO:0032036	myosin heavy chain binding	Mybpc3	IPI	PR:Q02566	Mouse	PMID:17075052
Molecular Function	GO:0005515	protein binding	MYBPC3	IPI	UniProtKB:Q5VU43-11	Human	PMID:21569246
Molecular Function	GO:0005515	protein binding	Mybpc3	IPI	UniProtKB:P68033|UniProtKB:Q02566	Mouse	MGI:MGI:5466448|PMID:22982234
Molecular Function	GO:0005515	protein binding	Mybpc3	IPI	UniProtKB:Q02566	Mouse	MGI:MGI:3695637|PMID:17075052
Molecular Function	GO:0005515	protein binding	Mybpc3	IPI	UniProtKB:P68135	Mouse	MGI:MGI:6093140|PMID:19011110
Molecular Function	GO:0008307	structural constituent of muscle	MYBPC3	IMP		Human	PMID:7493025
Cellular Component	GO:0031672	A band	MYBPC3	IDA		Human	PMID:10024460
Cellular Component	GO:0031672	A band	MYBPC3	IDA		Human	PMID:19850579
Cellular Component	GO:0031672	A band	Mybpc3	IDA		Mouse	PMID:10532952
Cellular Component	GO:0097512	cardiac myofibril	MYBPC3	IDA		Human	PMID:25771144
Cellular Component	GO:0030016	myofibril	Mybpc3	IDA		Mouse	PMID:10545522
Cellular Component	GO:0030017	sarcomere	MYBPC3	IDA		Human	PMID:10024460
Cellular Component	GO:0030017	sarcomere	Mybpc3	IDA		Mouse	PMID:17075052
Cellular Component	GO:0005863	striated muscle myosin thick filament	MYBPC3	IDA		Human	PMID:10024460
Cellular Component	GO:0005863	striated muscle myosin thick filament	Mybpc3	IDA		Rat	PMID:8799143|RGD:8553425
Biological Process	GO:0003210	cardiac atrium formation	mybpc3	IMP	ZFIN:ZDB-MRPHLNO-131127-1	Zfish	PMID:24047589
Biological Process	GO:0060048	cardiac muscle contraction	Mybpc3	IMP	MGI:MGI:3606208	Mouse	PMID:16380103
Biological Process	GO:0060048	cardiac muscle contraction	Mybpc3	IMP	MGI:MGI:2654420	Mouse	PMID:16224063
Biological Process	GO:0060048	cardiac muscle contraction	Mybpc3	IEP		Rat	PMID:8799143|RGD:8553425
Biological Process	GO:0003211	cardiac ventricle formation	mybpc3	IMP	ZFIN:ZDB-MRPHLNO-131127-1	Zfish	PMID:24047589
Biological Process	GO:0003007	heart morphogenesis	MYBPC3	IMP		Human	PMID:7493025
Biological Process	GO:0003007	heart morphogenesis	Mybpc3	IMP		Mouse	PMID:10532952
Biological Process	GO:0003007	heart morphogenesis	Mybpc3	IMP	MGI:MGI:2654420	Mouse	PMID:10545522
Biological Process	GO:0031034	myosin filament assembly	Mybpc3	IMP	MGI:MGI:3526881	Mouse	PMID:17254601
Biological Process	GO:0008016	regulation of heart contraction	Mybpc3	IMP	MGI:MGI:3526881	Mouse	PMID:14500336
Biological Process	GO:0008016	regulation of heart contraction	Mybpc3	IMP	MGI:MGI:2654420	Mouse	PMID:15059932
Biological Process	GO:0008016	regulation of heart contraction	Mybpc3	IMP	MGI:MGI:3526881	Mouse	PMID:15472117
Biological Process	GO:0002027	regulation of heart rate	Mybpc3	IMP		Mouse	PMID:10532952
Biological Process	GO:0002027	regulation of heart rate	mybpc3	IMP	ZFIN:ZDB-MRPHLNO-131127-1	Zfish	PMID:25281569
Biological Process	GO:0006942	regulation of striated muscle contraction	Mybpc3	IEP		Rat	PMID:8799143|RGD:8553425
Biological Process	GO:0045214	sarcomere organization	Mybpc3	IMP	MGI:MGI:3606208	Mouse	PMID:16380103
Biological Process	GO:0045214	sarcomere organization	Mybpc3	IMP	MGI:MGI:2654420	Mouse	PMID:16224063
Biological Process	GO:0045214	sarcomere organization	Mybpc3	IMP	MGI:MGI:2654420	Mouse	PMID:17075052
Biological Process	GO:0055010	ventricular cardiac muscle tissue morphogenesis	MYBPC3	IMP		Human	PMID:11815426
Biological Process	GO:0055010	ventricular cardiac muscle tissue morphogenesis	MYBPC3	IMP		Human	PMID:16754800
Biological Process	GO:0055010	ventricular cardiac muscle tissue morphogenesis	mybpc3	IMP	ZFIN:ZDB-MRPHLNO-131127-1	Zfish	PMID:25281569

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern