Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MUTYH
  • Mouse genes Mutyh
  • Rat genes Mutyh
  • Zfish genes mutyh
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Mutyh

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0019104	DNA N-glycosylase activity	Mutyh	IDA		Rat	PMID:14690527|RGD:1600194
Molecular Function	GO:0032407	MutSalpha complex binding	MUTYH	IDA		Human	PMID:11801590
Molecular Function	GO:0005515	protein binding	MUTYH	IPI	UniProtKB:P52701	Human	PMID:11801590
Molecular Function	GO:0000701	purine-specific mismatch base pair DNA N-glycosylase activity	MUTYH	IMP		Human	PMID:20848659
Cellular Component	GO:0005739	mitochondrion	Mutyh	HDA		Mouse	PMID:18614015
Cellular Component	GO:0005739	mitochondrion	Mutyh	IDA		Rat	PMID:12472901|RGD:628413
Cellular Component	GO:0005739	mitochondrion	Mutyh	IDA		Rat	PMID:14690527|RGD:1600194
Cellular Component	GO:0005654	nucleoplasm	MUTYH	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	Mutyh	IDA		Rat	PMID:14690527|RGD:1600194
Biological Process	GO:0060546	negative regulation of necroptotic process	Mutyh	IMP		Mouse	MGI:MGI:6378777|PMID:28059467
Biological Process	GO:0006979	response to oxidative stress	Mutyh	IDA		Rat	PMID:12472901|RGD:628413

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern