Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MTREX
  • Mouse genes Mtrex
  • Rat genes Mtrex
  • Zfish genes mtrex
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Mtrex

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005524	ATP binding	MTREX	IDA		Human	PMID:29844170
Molecular Function	GO:0005524	ATP binding	MTREX	IDA		Human	PMID:31358741
Molecular Function	GO:0005515	protein binding	MTREX	IPI	UniProtKB:Q99547	Human	PMID:15231747
Molecular Function	GO:0005515	protein binding	MTREX	IPI	UniProtKB:Q6NZY4	Human	PMID:16263084
Molecular Function	GO:0005515	protein binding	MTREX	IPI	UniProtKB:O15381	Human	PMID:16782053
Molecular Function	GO:0005515	protein binding	MTREX	IPI	UniProtKB:Q99547	Human	PMID:17412707
Molecular Function	GO:0005515	protein binding	MTREX	IPI	UniProtKB:O15381	Human	PMID:26166824
Molecular Function	GO:0005515	protein binding	MTREX	IPI	UniProtKB:Q6RFH5	Human	PMID:26456651
Molecular Function	GO:0005515	protein binding	MTREX	IPI	UniProtKB:O60293	Human	PMID:27871484
Molecular Function	GO:0005515	protein binding	MTREX	IPI	UniProtKB:Q9Y580	Human	PMID:27871484
Molecular Function	GO:0005515	protein binding	MTREX	IPI	UniProtKB:Q6NZY4	Human	PMID:27905398
Molecular Function	GO:0005515	protein binding	MTREX	IPI	UniProtKB:Q6RFH5	Human	PMID:29107693
Molecular Function	GO:0005515	protein binding	MTREX	IPI	UniProtKB:Q6NZY4	Human	PMID:29844170
Molecular Function	GO:0005515	protein binding	MTREX	IPI	UniProtKB:Q9H7Z3	Human	PMID:29902117
Molecular Function	GO:0005515	protein binding	MTREX	IPI	UniProtKB:Q9H7Z3	Human	PMID:30538148
Molecular Function	GO:0005515	protein binding	MTREX	IPI	UniProtKB:P24928,UniProtKB:Q9Y580	Human	PMID:30824372
Molecular Function	GO:0005515	protein binding	MTREX	IPI	UniProtKB:P50750,UniProtKB:Q4G0J3	Human	PMID:30824372
Molecular Function	GO:0005515	protein binding	MTREX	IPI	UniProtKB:Q9H7Z3	Human	PMID:30842217
Molecular Function	GO:0005515	protein binding	MTREX	IPI	UniProtKB:O15381	Human	PMID:31358741
Molecular Function	GO:0005515	protein binding	MTREX	IPI	UniProtKB:Q6NZY4	Human	PMID:31358741
Molecular Function	GO:0003723	RNA binding	MTREX	HDA		Human	PMID:22658674
Molecular Function	GO:0003724	RNA helicase activity	MTREX	IDA		Human	PMID:29844170
Molecular Function	GO:0003724	RNA helicase activity	MTREX	IDA		Human	PMID:29906447
Cellular Component	GO:0071013	catalytic step 2 spliceosome	MTREX	IDA		Human	PMID:11991638
Cellular Component	GO:0005654	nucleoplasm	MTREX	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	MTREX	IDA		Human	PMID:16263084
Cellular Component	GO:0005634	nucleus	MTREX	IDA		Human	PMID:16782053
Cellular Component	GO:0031499	TRAMP complex	MTREX	IDA		Human	PMID:21855801
Biological Process	GO:0006974	DNA damage response	MTREX	IMP		Human	PMID:29902117
Biological Process	GO:0031101	fin regeneration	mtrex	IMP	ZFIN:ZDB-GENO-071114-2	Zfish	PMID:17542649
Biological Process	GO:0000460	maturation of 5.8S rRNA	MTREX	IMP		Human	PMID:17412707
Biological Process	GO:0051781	positive regulation of cell division	mtrex	IMP	ZFIN:ZDB-GENO-071114-2	Zfish	PMID:17542649
Biological Process	GO:0006401	RNA catabolic process	MTREX	IDA		Human	PMID:29906447
Biological Process	GO:0006364	rRNA processing	MTREX	IMP		Human	PMID:29107693

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern