About   Help   FAQ
Gene Ontology Browser
Term Detail
GO term:catalytic step 2 spliceosome
Synonym: mammalian spliceosomal complex C
Synonym: mammalian spliceosomal complex C1
Synonym: yeast spliceosomal complex A2-2
GO id:GO:0071013
Definition:A spliceosomal complex that contains three snRNPs, including U5, bound to a splicing intermediate in which the first catalytic cleavage of the 5' splice site has occurred. The precise subunit composition differs significantly from that of the catalytic step 1, or activated, spliceosome, and includes many proteins in addition to those found in the associated snRNPs.
Number of paths to term: 22

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


Gene_Ontology
        is-acellular_component
                is-acell
                        part-ofcell part
                                is-aintracellular
                                        part-ofintracellular part
                                                is-aintracellular organelle
                                                        is-aintracellular membrane-bounded organelle
                                                                is-anucleus
                                                                        part-ofnuclear part
                                                                                is-aspliceosomal complex
                                                                                        is-acatalytic step 1 spliceosome +
                                                                                        is-acatalytic step 2 spliceosome [GO:0071013] (71 genes, 74 annotations)
                                                                                                is-aU12-type catalytic step 2 spliceosome
                                                                                                is-aU2-type catalytic step 2 spliceosome
                                                                                        is-apost-mRNA release spliceosomal complex +
                                                                                        is-apost-spliceosomal complex +
                                                                                        is-aprecatalytic spliceosome +
                                                                                        is-aprespliceosome +
                                                                                        is-asupraspliceosomal complex
                                                                                        is-atrans spliceosomal complex
                                                                                        is-aU12-type spliceosomal complex +
                                                                                        is-aU2-type spliceosomal complex +


Gene_Ontology
        is-acellular_component
                is-acell
                        part-ofcell part
                                is-aintracellular
                                        part-ofintracellular part
                                                is-aintracellular organelle
                                                        part-ofintracellular organelle part
                                                                is-anuclear part
                                                                        is-aspliceosomal complex
                                                                                is-acatalytic step 1 spliceosome +
                                                                                is-acatalytic step 2 spliceosome [GO:0071013] (71 genes, 74 annotations)
                                                                                        is-aU12-type catalytic step 2 spliceosome
                                                                                        is-aU2-type catalytic step 2 spliceosome
                                                                                is-apost-mRNA release spliceosomal complex +
                                                                                is-apost-spliceosomal complex +
                                                                                is-aprecatalytic spliceosome +
                                                                                is-aprespliceosome +
                                                                                is-asupraspliceosomal complex
                                                                                is-atrans spliceosomal complex
                                                                                is-aU12-type spliceosomal complex +
                                                                                is-aU2-type spliceosomal complex +


Gene_Ontology
        is-acellular_component
                is-acell
                        part-ofcell part
                                is-aintracellular
                                        part-ofintracellular part
                                                is-aintracellular organelle part
                                                        is-anuclear part
                                                                is-aspliceosomal complex
                                                                        is-acatalytic step 1 spliceosome +
                                                                        is-acatalytic step 2 spliceosome [GO:0071013] (71 genes, 74 annotations)
                                                                                is-aU12-type catalytic step 2 spliceosome
                                                                                is-aU2-type catalytic step 2 spliceosome
                                                                        is-apost-mRNA release spliceosomal complex +
                                                                        is-apost-spliceosomal complex +
                                                                        is-aprecatalytic spliceosome +
                                                                        is-aprespliceosome +
                                                                        is-asupraspliceosomal complex
                                                                        is-atrans spliceosomal complex
                                                                        is-aU12-type spliceosomal complex +
                                                                        is-aU2-type spliceosomal complex +


Gene_Ontology
        is-acellular_component
                is-acell
                        part-ofcell part
                                is-aintracellular
                                        part-ofintracellular part
                                                is-aribonucleoprotein complex
                                                        is-aspliceosomal complex
                                                                is-acatalytic step 1 spliceosome +
                                                                is-acatalytic step 2 spliceosome [GO:0071013] (71 genes, 74 annotations)
                                                                        is-aU12-type catalytic step 2 spliceosome
                                                                        is-aU2-type catalytic step 2 spliceosome
                                                                is-apost-mRNA release spliceosomal complex +
                                                                is-apost-spliceosomal complex +
                                                                is-aprecatalytic spliceosome +
                                                                is-aprespliceosome +
                                                                is-asupraspliceosomal complex
                                                                is-atrans spliceosomal complex
                                                                is-aU12-type spliceosomal complex +
                                                                is-aU2-type spliceosomal complex +


Gene_Ontology
        is-acellular_component
                is-acell
                        part-ofcell part
                                is-aintracellular part
                                        is-aintracellular organelle
                                                is-aintracellular membrane-bounded organelle
                                                        is-anucleus
                                                                part-ofnuclear part
                                                                        is-aspliceosomal complex
                                                                                is-acatalytic step 1 spliceosome +
                                                                                is-acatalytic step 2 spliceosome [GO:0071013] (71 genes, 74 annotations)
                                                                                        is-aU12-type catalytic step 2 spliceosome
                                                                                        is-aU2-type catalytic step 2 spliceosome
                                                                                is-apost-mRNA release spliceosomal complex +
                                                                                is-apost-spliceosomal complex +
                                                                                is-aprecatalytic spliceosome +
                                                                                is-aprespliceosome +
                                                                                is-asupraspliceosomal complex
                                                                                is-atrans spliceosomal complex
                                                                                is-aU12-type spliceosomal complex +
                                                                                is-aU2-type spliceosomal complex +


Gene_Ontology
        is-acellular_component
                is-acell
                        part-ofcell part
                                is-aintracellular part
                                        is-aintracellular organelle
                                                part-ofintracellular organelle part
                                                        is-anuclear part
                                                                is-aspliceosomal complex
                                                                        is-acatalytic step 1 spliceosome +
                                                                        is-acatalytic step 2 spliceosome [GO:0071013] (71 genes, 74 annotations)
                                                                                is-aU12-type catalytic step 2 spliceosome
                                                                                is-aU2-type catalytic step 2 spliceosome
                                                                        is-apost-mRNA release spliceosomal complex +
                                                                        is-apost-spliceosomal complex +
                                                                        is-aprecatalytic spliceosome +
                                                                        is-aprespliceosome +
                                                                        is-asupraspliceosomal complex
                                                                        is-atrans spliceosomal complex
                                                                        is-aU12-type spliceosomal complex +
                                                                        is-aU2-type spliceosomal complex +


Gene_Ontology
        is-acellular_component
                is-acell
                        part-ofcell part
                                is-aintracellular part
                                        is-aintracellular organelle part
                                                is-anuclear part
                                                        is-aspliceosomal complex
                                                                is-acatalytic step 1 spliceosome +
                                                                is-acatalytic step 2 spliceosome [GO:0071013] (71 genes, 74 annotations)
                                                                        is-aU12-type catalytic step 2 spliceosome
                                                                        is-aU2-type catalytic step 2 spliceosome
                                                                is-apost-mRNA release spliceosomal complex +
                                                                is-apost-spliceosomal complex +
                                                                is-aprecatalytic spliceosome +
                                                                is-aprespliceosome +
                                                                is-asupraspliceosomal complex
                                                                is-atrans spliceosomal complex
                                                                is-aU12-type spliceosomal complex +
                                                                is-aU2-type spliceosomal complex +


Gene_Ontology
        is-acellular_component
                is-acell
                        part-ofcell part
                                is-aintracellular part
                                        is-aribonucleoprotein complex
                                                is-aspliceosomal complex
                                                        is-acatalytic step 1 spliceosome +
                                                        is-acatalytic step 2 spliceosome [GO:0071013] (71 genes, 74 annotations)
                                                                is-aU12-type catalytic step 2 spliceosome
                                                                is-aU2-type catalytic step 2 spliceosome
                                                        is-apost-mRNA release spliceosomal complex +
                                                        is-apost-spliceosomal complex +
                                                        is-aprecatalytic spliceosome +
                                                        is-aprespliceosome +
                                                        is-asupraspliceosomal complex
                                                        is-atrans spliceosomal complex
                                                        is-aU12-type spliceosomal complex +
                                                        is-aU2-type spliceosomal complex +


Gene_Ontology
        is-acellular_component
                is-acell part
                        is-aintracellular
                                part-ofintracellular part
                                        is-aintracellular organelle
                                                is-aintracellular membrane-bounded organelle
                                                        is-anucleus
                                                                part-ofnuclear part
                                                                        is-aspliceosomal complex
                                                                                is-acatalytic step 1 spliceosome +
                                                                                is-acatalytic step 2 spliceosome [GO:0071013] (71 genes, 74 annotations)
                                                                                        is-aU12-type catalytic step 2 spliceosome
                                                                                        is-aU2-type catalytic step 2 spliceosome
                                                                                is-apost-mRNA release spliceosomal complex +
                                                                                is-apost-spliceosomal complex +
                                                                                is-aprecatalytic spliceosome +
                                                                                is-aprespliceosome +
                                                                                is-asupraspliceosomal complex
                                                                                is-atrans spliceosomal complex
                                                                                is-aU12-type spliceosomal complex +
                                                                                is-aU2-type spliceosomal complex +


Gene_Ontology
        is-acellular_component
                is-acell part
                        is-aintracellular
                                part-ofintracellular part
                                        is-aintracellular organelle
                                                part-ofintracellular organelle part
                                                        is-anuclear part
                                                                is-aspliceosomal complex
                                                                        is-acatalytic step 1 spliceosome +
                                                                        is-acatalytic step 2 spliceosome [GO:0071013] (71 genes, 74 annotations)
                                                                                is-aU12-type catalytic step 2 spliceosome
                                                                                is-aU2-type catalytic step 2 spliceosome
                                                                        is-apost-mRNA release spliceosomal complex +
                                                                        is-apost-spliceosomal complex +
                                                                        is-aprecatalytic spliceosome +
                                                                        is-aprespliceosome +
                                                                        is-asupraspliceosomal complex
                                                                        is-atrans spliceosomal complex
                                                                        is-aU12-type spliceosomal complex +
                                                                        is-aU2-type spliceosomal complex +


Gene_Ontology
        is-acellular_component
                is-acell part
                        is-aintracellular
                                part-ofintracellular part
                                        is-aintracellular organelle part
                                                is-anuclear part
                                                        is-aspliceosomal complex
                                                                is-acatalytic step 1 spliceosome +
                                                                is-acatalytic step 2 spliceosome [GO:0071013] (71 genes, 74 annotations)
                                                                        is-aU12-type catalytic step 2 spliceosome
                                                                        is-aU2-type catalytic step 2 spliceosome
                                                                is-apost-mRNA release spliceosomal complex +
                                                                is-apost-spliceosomal complex +
                                                                is-aprecatalytic spliceosome +
                                                                is-aprespliceosome +
                                                                is-asupraspliceosomal complex
                                                                is-atrans spliceosomal complex
                                                                is-aU12-type spliceosomal complex +
                                                                is-aU2-type spliceosomal complex +


Gene_Ontology
        is-acellular_component
                is-acell part
                        is-aintracellular
                                part-ofintracellular part
                                        is-aribonucleoprotein complex
                                                is-aspliceosomal complex
                                                        is-acatalytic step 1 spliceosome +
                                                        is-acatalytic step 2 spliceosome [GO:0071013] (71 genes, 74 annotations)
                                                                is-aU12-type catalytic step 2 spliceosome
                                                                is-aU2-type catalytic step 2 spliceosome
                                                        is-apost-mRNA release spliceosomal complex +
                                                        is-apost-spliceosomal complex +
                                                        is-aprecatalytic spliceosome +
                                                        is-aprespliceosome +
                                                        is-asupraspliceosomal complex
                                                        is-atrans spliceosomal complex
                                                        is-aU12-type spliceosomal complex +
                                                        is-aU2-type spliceosomal complex +


Gene_Ontology
        is-acellular_component
                is-acell part
                        is-aintracellular part
                                is-aintracellular organelle
                                        is-aintracellular membrane-bounded organelle
                                                is-anucleus
                                                        part-ofnuclear part
                                                                is-aspliceosomal complex
                                                                        is-acatalytic step 1 spliceosome +
                                                                        is-acatalytic step 2 spliceosome [GO:0071013] (71 genes, 74 annotations)
                                                                                is-aU12-type catalytic step 2 spliceosome
                                                                                is-aU2-type catalytic step 2 spliceosome
                                                                        is-apost-mRNA release spliceosomal complex +
                                                                        is-apost-spliceosomal complex +
                                                                        is-aprecatalytic spliceosome +
                                                                        is-aprespliceosome +
                                                                        is-asupraspliceosomal complex
                                                                        is-atrans spliceosomal complex
                                                                        is-aU12-type spliceosomal complex +
                                                                        is-aU2-type spliceosomal complex +


Gene_Ontology
        is-acellular_component
                is-acell part
                        is-aintracellular part
                                is-aintracellular organelle
                                        part-ofintracellular organelle part
                                                is-anuclear part
                                                        is-aspliceosomal complex
                                                                is-acatalytic step 1 spliceosome +
                                                                is-acatalytic step 2 spliceosome [GO:0071013] (71 genes, 74 annotations)
                                                                        is-aU12-type catalytic step 2 spliceosome
                                                                        is-aU2-type catalytic step 2 spliceosome
                                                                is-apost-mRNA release spliceosomal complex +
                                                                is-apost-spliceosomal complex +
                                                                is-aprecatalytic spliceosome +
                                                                is-aprespliceosome +
                                                                is-asupraspliceosomal complex
                                                                is-atrans spliceosomal complex
                                                                is-aU12-type spliceosomal complex +
                                                                is-aU2-type spliceosomal complex +


Gene_Ontology
        is-acellular_component
                is-acell part
                        is-aintracellular part
                                is-aintracellular organelle part
                                        is-anuclear part
                                                is-aspliceosomal complex
                                                        is-acatalytic step 1 spliceosome +
                                                        is-acatalytic step 2 spliceosome [GO:0071013] (71 genes, 74 annotations)
                                                                is-aU12-type catalytic step 2 spliceosome
                                                                is-aU2-type catalytic step 2 spliceosome
                                                        is-apost-mRNA release spliceosomal complex +
                                                        is-apost-spliceosomal complex +
                                                        is-aprecatalytic spliceosome +
                                                        is-aprespliceosome +
                                                        is-asupraspliceosomal complex
                                                        is-atrans spliceosomal complex
                                                        is-aU12-type spliceosomal complex +
                                                        is-aU2-type spliceosomal complex +


Gene_Ontology
        is-acellular_component
                is-acell part
                        is-aintracellular part
                                is-aribonucleoprotein complex
                                        is-aspliceosomal complex
                                                is-acatalytic step 1 spliceosome +
                                                is-acatalytic step 2 spliceosome [GO:0071013] (71 genes, 74 annotations)
                                                        is-aU12-type catalytic step 2 spliceosome
                                                        is-aU2-type catalytic step 2 spliceosome
                                                is-apost-mRNA release spliceosomal complex +
                                                is-apost-spliceosomal complex +
                                                is-aprecatalytic spliceosome +
                                                is-aprespliceosome +
                                                is-asupraspliceosomal complex
                                                is-atrans spliceosomal complex
                                                is-aU12-type spliceosomal complex +
                                                is-aU2-type spliceosomal complex +


Gene_Ontology
        is-acellular_component
                is-amacromolecular complex
                        is-aribonucleoprotein complex
                                is-aspliceosomal complex
                                        is-acatalytic step 1 spliceosome +
                                        is-acatalytic step 2 spliceosome [GO:0071013] (71 genes, 74 annotations)
                                                is-aU12-type catalytic step 2 spliceosome
                                                is-aU2-type catalytic step 2 spliceosome
                                        is-apost-mRNA release spliceosomal complex +
                                        is-apost-spliceosomal complex +
                                        is-aprecatalytic spliceosome +
                                        is-aprespliceosome +
                                        is-asupraspliceosomal complex
                                        is-atrans spliceosomal complex
                                        is-aU12-type spliceosomal complex +
                                        is-aU2-type spliceosomal complex +


Gene_Ontology
        is-acellular_component
                is-aorganelle
                        is-aintracellular organelle
                                is-aintracellular membrane-bounded organelle
                                        is-anucleus
                                                part-ofnuclear part
                                                        is-aspliceosomal complex
                                                                is-acatalytic step 1 spliceosome +
                                                                is-acatalytic step 2 spliceosome [GO:0071013] (71 genes, 74 annotations)
                                                                        is-aU12-type catalytic step 2 spliceosome
                                                                        is-aU2-type catalytic step 2 spliceosome
                                                                is-apost-mRNA release spliceosomal complex +
                                                                is-apost-spliceosomal complex +
                                                                is-aprecatalytic spliceosome +
                                                                is-aprespliceosome +
                                                                is-asupraspliceosomal complex
                                                                is-atrans spliceosomal complex
                                                                is-aU12-type spliceosomal complex +
                                                                is-aU2-type spliceosomal complex +


Gene_Ontology
        is-acellular_component
                is-aorganelle
                        is-aintracellular organelle
                                part-ofintracellular organelle part
                                        is-anuclear part
                                                is-aspliceosomal complex
                                                        is-acatalytic step 1 spliceosome +
                                                        is-acatalytic step 2 spliceosome [GO:0071013] (71 genes, 74 annotations)
                                                                is-aU12-type catalytic step 2 spliceosome
                                                                is-aU2-type catalytic step 2 spliceosome
                                                        is-apost-mRNA release spliceosomal complex +
                                                        is-apost-spliceosomal complex +
                                                        is-aprecatalytic spliceosome +
                                                        is-aprespliceosome +
                                                        is-asupraspliceosomal complex
                                                        is-atrans spliceosomal complex
                                                        is-aU12-type spliceosomal complex +
                                                        is-aU2-type spliceosomal complex +


Gene_Ontology
        is-acellular_component
                is-aorganelle
                        is-amembrane-bounded organelle
                                is-aintracellular membrane-bounded organelle
                                        is-anucleus
                                                part-ofnuclear part
                                                        is-aspliceosomal complex
                                                                is-acatalytic step 1 spliceosome +
                                                                is-acatalytic step 2 spliceosome [GO:0071013] (71 genes, 74 annotations)
                                                                        is-aU12-type catalytic step 2 spliceosome
                                                                        is-aU2-type catalytic step 2 spliceosome
                                                                is-apost-mRNA release spliceosomal complex +
                                                                is-apost-spliceosomal complex +
                                                                is-aprecatalytic spliceosome +
                                                                is-aprespliceosome +
                                                                is-asupraspliceosomal complex
                                                                is-atrans spliceosomal complex
                                                                is-aU12-type spliceosomal complex +
                                                                is-aU2-type spliceosomal complex +


Gene_Ontology
        is-acellular_component
                is-aorganelle
                        part-oforganelle part
                                is-aintracellular organelle part
                                        is-anuclear part
                                                is-aspliceosomal complex
                                                        is-acatalytic step 1 spliceosome +
                                                        is-acatalytic step 2 spliceosome [GO:0071013] (71 genes, 74 annotations)
                                                                is-aU12-type catalytic step 2 spliceosome
                                                                is-aU2-type catalytic step 2 spliceosome
                                                        is-apost-mRNA release spliceosomal complex +
                                                        is-apost-spliceosomal complex +
                                                        is-aprecatalytic spliceosome +
                                                        is-aprespliceosome +
                                                        is-asupraspliceosomal complex
                                                        is-atrans spliceosomal complex
                                                        is-aU12-type spliceosomal complex +
                                                        is-aU2-type spliceosomal complex +


Gene_Ontology
        is-acellular_component
                is-aorganelle part
                        is-aintracellular organelle part
                                is-anuclear part
                                        is-aspliceosomal complex
                                                is-acatalytic step 1 spliceosome +
                                                is-acatalytic step 2 spliceosome [GO:0071013] (71 genes, 74 annotations)
                                                        is-aU12-type catalytic step 2 spliceosome
                                                        is-aU2-type catalytic step 2 spliceosome
                                                is-apost-mRNA release spliceosomal complex +
                                                is-apost-spliceosomal complex +
                                                is-aprecatalytic spliceosome +
                                                is-aprespliceosome +
                                                is-asupraspliceosomal complex
                                                is-atrans spliceosomal complex
                                                is-aU12-type spliceosomal complex +
                                                is-aU2-type spliceosomal complex +


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
11/18/2014
MGI 5.20
The Jackson Laboratory