Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MTR
  • Mouse genes Mtr
  • Rat genes Mtr
  • Zfish genes mtr
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Mtr

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0016597	amino acid binding	Mtr	IDA		Rat	PMID:11730351|RGD:1601423
Molecular Function	GO:0005542	folic acid binding	Mtr	IDA		Rat	PMID:11730351|RGD:1601423
Molecular Function	GO:0008705	methionine synthase activity	MTR	IDA		Human	PMID:16769880
Molecular Function	GO:0008705	methionine synthase activity	MTR	IMP		Human	PMID:23825108
Molecular Function	GO:0008705	methionine synthase activity	Mtr	IMP	MGI:MGI:2180496	Mouse	PMID:11158293
Molecular Function	GO:0008705	methionine synthase activity	Mtr	IDA		Rat	PMID:11730351|RGD:1601423
Molecular Function	GO:0008705	methionine synthase activity	Mtr	IDA		Rat	PMID:20424322|RGD:10054082
Molecular Function	GO:0008705	methionine synthase activity	Mtr	IMP		Rat	PMID:21121936|RGD:7207080
Molecular Function	GO:0008705	methionine synthase activity	Mtr	IDA		Rat	PMID:9972236|RGD:633492
Molecular Function	GO:0008168	methyltransferase activity	Mtr	IDA		Rat	PMID:15845641|RGD:1359026
Molecular Function	GO:0005515	protein binding	MTR	IPI	UniProtKB:Q9UBK8	Human	PMID:17288554
Molecular Function	GO:0005515	protein binding	MTR	IPI	UniProtKB:Q9Y4U1	Human	PMID:23825108
Molecular Function	GO:0005515	protein binding	MTR	IPI	UniProtKB:Q9H3L0	Human	PMID:27771510
Molecular Function	GO:0005515	protein binding	MTR	IPI	UniProtKB:Q9UBK8	Human	PMID:27771510
Molecular Function	GO:0005515	protein binding	MTR	IPI	UniProtKB:Q9Y4U1	Human	PMID:27771510
Cellular Component	GO:0005829	cytosol	MTR	IDA		Human	GO_REF:0000052
Biological Process	GO:0031103	axon regeneration	Mtr	IMP		Rat	PMID:20424322|RGD:10054082
Biological Process	GO:0061431	cellular response to methionine	Mtr	IEP		Rat	PMID:1201245|RGD:6893692
Biological Process	GO:0071732	cellular response to nitric oxide	Mtr	IDA		Rat	PMID:20424322|RGD:10054082
Biological Process	GO:0009235	cobalamin metabolic process	MTR	IMP		Human	PMID:23825108
Biological Process	GO:0009235	cobalamin metabolic process	Mtr	IMP	MGI:MGI:2180496	Mouse	PMID:11158293
Biological Process	GO:0050667	homocysteine metabolic process	Mtr	IDA		Rat	PMID:11730351|RGD:1601423
Biological Process	GO:0050667	homocysteine metabolic process	Mtr	IMP		Rat	PMID:21121936|RGD:7207080
Biological Process	GO:0009086	methionine biosynthetic process	MTR	IMP		Human	PMID:23825108
Biological Process	GO:0009086	methionine biosynthetic process	Mtr	IMP	MGI:MGI:2180496	Mouse	PMID:11158293
Biological Process	GO:0009086	methionine biosynthetic process	Mtr	IDA		Rat	PMID:11730351|RGD:1601423
Biological Process	GO:0009086	methionine biosynthetic process	Mtr	IDA		Rat	PMID:15845641|RGD:1359026
Biological Process	GO:0006555	methionine metabolic process	Mtr	IMP		Rat	PMID:21121936|RGD:7207080
Biological Process	GO:0006479	protein methylation	Mtr	IDA		Rat	PMID:15845641|RGD:1359026
Biological Process	GO:0048678	response to axon injury	Mtr	IDA		Rat	PMID:20424322|RGD:10054082
Biological Process	GO:0046653	tetrahydrofolate metabolic process	Mtr	IDA		Rat	PMID:11730351|RGD:1601423
Biological Process	GO:0046653	tetrahydrofolate metabolic process	Mtr	IMP		Rat	PMID:21121936|RGD:7207080

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern