Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MTLN
  • Mouse genes Mtln
  • Rat genes
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Mtln

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	MTLN	IPI	UniProtKB:P06576	Human	PMID:32243843
Molecular Function	GO:0005515	protein binding	MTLN	IPI	UniProtKB:P55084	Human	PMID:32243843
Molecular Function	GO:0005515	protein binding	Mtln	IPI	UniProtKB:Q9DCN2	Mouse	MGI:MGI:6283949|PMID:30796188
Molecular Function	GO:0005515	protein binding	Mtln	IPI	UniProtKB:Q8BMS1|UniProtKB:Q99JY0	Mouse	MGI:MGI:6278482|PMID:29949755
Cellular Component	GO:0005743	mitochondrial inner membrane	Mtln	IDA		Mouse	MGI:MGI:6393021|PMID:31296841
Cellular Component	GO:0005743	mitochondrial inner membrane	Mtln	IDA		Mouse	MGI:MGI:6278482|PMID:29949755
Cellular Component	GO:0005743	mitochondrial inner membrane	Mtln	IDA		Mouse	MGI:MGI:6189513|PMID:29949756
Cellular Component	GO:0005739	mitochondrion	MTLN	IDA		Human	PMID:32243843
Cellular Component	GO:0005739	mitochondrion	Mtln	IDA		Mouse	MGI:MGI:6283949|PMID:30796188
Cellular Component	GO:0005739	mitochondrion	Mtln	IDA		Mouse	MGI:MGI:6694358|PMID:32393776
Biological Process	GO:0044255	cellular lipid metabolic process	Mtln	IMP		Mouse	MGI:MGI:6283949|PMID:30796188
Biological Process	GO:0045333	cellular respiration	Mtln	IMP		Mouse	MGI:MGI:6393021|PMID:31296841
Biological Process	GO:0006635	fatty acid beta-oxidation	MTLN	IMP		Human	PMID:32243843
Biological Process	GO:0032000	positive regulation of fatty acid beta-oxidation	Mtln	IMP		Mouse	MGI:MGI:6278482|PMID:29949755
Biological Process	GO:0010918	positive regulation of mitochondrial membrane potential	MTLN	IDA		Human	PMID:29949756
Biological Process	GO:0031334	positive regulation of protein-containing complex assembly	Mtln	IMP		Mouse	MGI:MGI:6189513|PMID:29949756
Biological Process	GO:0051284	positive regulation of sequestering of calcium ion	MTLN	IDA		Human	PMID:29949756
Biological Process	GO:0051284	positive regulation of sequestering of calcium ion	Mtln	IDA		Mouse	MGI:MGI:6189513|PMID:29949756
Biological Process	GO:0051146	striated muscle cell differentiation	Mtln	IMP		Mouse	MGI:MGI:6393021|PMID:31296841
Biological Process	GO:0070328	triglyceride homeostasis	MTLN	IMP		Human	PMID:32243843

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern