Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MST1R
  • Mouse genes Mst1r
  • Rat genes Mst1r
  • Zfish genes mst1ra,mst1rb
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Mst1r

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0019899	enzyme binding	MST1R	IPI	UniProtKB:Q12891	Human	PMID:12676986
Molecular Function	GO:0005515	protein binding	MST1R	IPI	UniProtKB:O15031	Human	PMID:15184888
Molecular Function	GO:0005515	protein binding	MST1R	IPI	UniProtKB:O43157	Human	PMID:15184888
Molecular Function	GO:0005515	protein binding	MST1R	IPI	UniProtKB:Q9ULL4	Human	PMID:15184888
Molecular Function	GO:0005515	protein binding	MST1R	IPI	UniProtKB:P26927	Human	PMID:22087277
Molecular Function	GO:0005515	protein binding	MST1R	IPI	UniProtKB:P26927	Human	PMID:25193665
Cellular Component	GO:0009986	cell surface	MST1R	HDA		Human	PMID:19581412
Cellular Component	GO:0005886	plasma membrane	Mst1r	IDA		Mouse	PMID:12606483
Cellular Component	GO:0001725	stress fiber	Mst1r	IDA		Mouse	PMID:12606483
Cellular Component	GO:0005773	vacuole	Mst1r	IDA		Mouse	PMID:25049204
Biological Process	GO:0030282	bone mineralization	mst1rb	IMP	ZFIN:ZDB-MRPHLNO-121115-2	Zfish	PMID:22787265
Biological Process	GO:0030282	bone mineralization	mst1rb	IMP	ZFIN:ZDB-MRPHLNO-121115-3	Zfish	PMID:22787265
Biological Process	GO:0043406	positive regulation of MAP kinase activity	MST1R	IDA		Human	PMID:12676986
Biological Process	GO:0051897	positive regulation of protein kinase B signaling	MST1R	IDA		Human	PMID:12676986
Biological Process	GO:0009615	response to virus	MST1R	IDA		Human	PMID:12676986
Biological Process	GO:0009615	response to virus	Mst1r	IMP	MGI:MGI:1857882	Mouse	PMID:10508511

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern