Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MSH4
  • Mouse genes Msh4
  • Rat genes Msh4
  • Zfish genes msh4
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Msh4

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	MSH4	IPI	UniProtKB:O43196	Human	PMID:16397227
Molecular Function	GO:0005515	protein binding	MSH4	IPI	UniProtKB:O43196	Human	PMID:22401567
Molecular Function	GO:0005515	protein binding	MSH4	IPI	UniProtKB:O00303	Human	PMID:23725059
Cellular Component	GO:0005694	chromosome	Msh4	IDA		Mouse	MGI:MGI:6272683|PMID:30272023
Cellular Component	GO:0000793	condensed chromosome	Msh4	IDA		Mouse	PMID:10809667
Cellular Component	GO:0000794	condensed nuclear chromosome	Msh4	IDA		Mouse	PMID:18316482
Cellular Component	GO:0000794	condensed nuclear chromosome	Msh4	IDA		Mouse	PMID:23555294
Cellular Component	GO:0000794	condensed nuclear chromosome	Msh4	IDA		Mouse	PMID:22164254
Cellular Component	GO:0005634	nucleus	Msh4	IDA		Mouse	PMID:10809667
Cellular Component	GO:0005634	nucleus	Msh4	IDA		Mouse	PMID:30718482
Cellular Component	GO:0005713	recombination nodule	Msh4	IDA		Mouse	PMID:27760146
Cellular Component	GO:0000795	synaptonemal complex	Msh4	IDA		Mouse	PMID:10809667
Cellular Component	GO:0000795	synaptonemal complex	Msh4	IDA		Mouse	PMID:16260499
Biological Process	GO:0007292	female gamete generation	Msh4	IMP	MGI:MGI:2179034	Mouse	PMID:10809667
Biological Process	GO:0007129	homologous chromosome pairing at meiosis	Msh4	IMP	MGI:MGI:2179034	Mouse	PMID:15467367
Biological Process	GO:0007129	homologous chromosome pairing at meiosis	Msh4	IMP	MGI:MGI:2179034	Mouse	PMID:10809667
Biological Process	GO:0051321	meiotic cell cycle	Msh4	IDA		Mouse	PMID:10809667
Biological Process	GO:0051321	meiotic cell cycle	Msh4	IMP	MGI:MGI:2179034	Mouse	PMID:10809667
Biological Process	GO:0001541	ovarian follicle development	Msh4	IMP	MGI:MGI:2179034	Mouse	PMID:10809667
Biological Process	GO:0007283	spermatogenesis	Msh4	IMP	MGI:MGI:2179034	Mouse	PMID:10809667

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern