Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MSC
  • Mouse genes Msc
  • Rat genes Msc
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Msc

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	Msc	IMP		Mouse	MGI:MGI:1328714|PMID:9892671
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	Msc	IDA		Mouse	MGI:MGI:1328714|PMID:9892671
Molecular Function	GO:0005515	protein binding	MSC	IPI	UniProtKB:P15884-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MSC	IPI	UniProtKB:P40425	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MSC	IPI	UniProtKB:Q8TBB1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MSC	IPI	UniProtKB:Q99081-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MSC	IPI	UniProtKB:Q9H8Y8	Human	PMID:32296183
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	MSC	IDA		Human	PMID:9584154
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	Msc	IDA		Mouse	MGI:MGI:1328714|PMID:9892671
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	MSC	IDA		Human	PMID:28473536
Cellular Component	GO:0005654	nucleoplasm	MSC	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	Msc	IDA		Mouse	PMID:19796622
Biological Process	GO:0014707	branchiomeric skeletal muscle development	Msc	IGI	UniProtKB:O35437	Mouse	MGI:MGI:3653784|PMID:12493912
Biological Process	GO:1990830	cellular response to leukemia inhibitory factor	Msc	IEP		Mouse	PMID:20439489
Biological Process	GO:0060539	diaphragm development	Msc	IGI	UniProtKB:O35437	Mouse	MGI:MGI:3653784|PMID:12493912
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Msc	IDA		Mouse	MGI:MGI:1328714|PMID:9892671
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Msc	IMP		Mouse	MGI:MGI:1328714|PMID:9892671
Biological Process	GO:0060021	roof of mouth development	Msc	IGI	UniProtKB:O35437	Mouse	MGI:MGI:3653784|PMID:12493912

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern