Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MRC2
  • Mouse genes Mrc2
  • Rat genes Mrc2
  • Zfish genes mrc2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Mrc2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005518	collagen binding	MRC2	IDA		Human	PMID:10636902
Molecular Function	GO:0005518	collagen binding	MRC2	IDA		Human	PMID:12972549
Molecular Function	GO:0005518	collagen binding	Mrc2	IPI	RGD:61817	Rat	PMID:15817460|RGD:1579812
Molecular Function	GO:0005515	protein binding	MRC2	IPI	UniProtKB:P02454	Human	PMID:26481812
Molecular Function	GO:0005515	protein binding	MRC2	IPI	UniProtKB:P00749	Human	PMID:7904248
Cellular Component	GO:0005925	focal adhesion	MRC2	HDA		Human	PMID:21423176
Cellular Component	GO:0016020	membrane	MRC2	HDA		Human	PMID:16210410
Biological Process	GO:0030574	collagen catabolic process	MRC2	IDA		Human	PMID:12972549
Biological Process	GO:0001649	osteoblast differentiation	MRC2	HDA		Human	PMID:16210410

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern