Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MRAS
  • Mouse genes Mras
  • Rat genes Mras
  • Zfish genes mrasa,mrasb
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Mras

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0030742	GTP-dependent protein binding	MRAS	IPI	UniProtKB:Q92565	Human	PMID:10934204
Molecular Function	GO:0003924	GTPase activity	MRAS	IMP		Human	PMID:28289718
Molecular Function	GO:0005515	protein binding	MRAS	IPI	UniProtKB:Q9UQ13	Human	PMID:25137548
Molecular Function	GO:0005515	protein binding	Mras	IPI	UniProtKB:O08773	Rat	PMID:19319189|RGD:8554645
Biological Process	GO:1990830	cellular response to leukemia inhibitory factor	Mras	IEP		Mouse	PMID:20439489
Biological Process	GO:0007265	Ras protein signal transduction	MRAS	IMP		Human	PMID:28289718

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern