Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MMRN2
  • Mouse genes Mmrn2
  • Rat genes Mmrn2
  • Zfish genes mmrn2a,mmrn2b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Mmrn2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	MMRN2	IPI	UniProtKB:P15692	Human	PMID:22020326
Molecular Function	GO:0005515	protein binding	MMRN2	IPI	UniProtKB:Q6NTF9-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Mmrn2	IPI	UniProtKB:Q8VCP9	Mouse	PMID:25745997
Cellular Component	GO:0005604	basement membrane	Mmrn2	IDA		Mouse	PMID:18757743
Cellular Component	GO:0062023	collagen-containing extracellular matrix	MMRN2	HDA		Human	PMID:23979707
Cellular Component	GO:0062023	collagen-containing extracellular matrix	MMRN2	IDA		Human	PMID:23979707
Cellular Component	GO:0062023	collagen-containing extracellular matrix	MMRN2	HDA		Human	PMID:28675934
Cellular Component	GO:0062023	collagen-containing extracellular matrix	Mmrn2	HDA		Mouse	MGI:MGI:6201834|PMID:22159717
Cellular Component	GO:0070062	extracellular exosome	MMRN2	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	MMRN2	HDA		Human	PMID:23533145
Cellular Component	GO:0005615	extracellular space	MMRN2	IDA		Human	PMID:11559704
Biological Process	GO:0002042	cell migration involved in sprouting angiogenesis	Mmrn2	IMP		Mouse	PMID:25745997
Biological Process	GO:1903588	negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis	MMRN2	IDA		Human	PMID:25745997
Biological Process	GO:1903588	negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis	Mmrn2	IDA		Mouse	MGI:MGI:5780028|PMID:25745997
Biological Process	GO:0030336	negative regulation of cell migration	MMRN2	IDA		Human	PMID:22020326
Biological Process	GO:0090051	negative regulation of cell migration involved in sprouting angiogenesis	MMRN2	IDA		Human	PMID:22020326
Biological Process	GO:0008285	negative regulation of cell population proliferation	MMRN2	IDA		Human	PMID:22020326
Biological Process	GO:0008285	negative regulation of cell population proliferation	Mmrn2	IDA		Mouse	MGI:MGI:5780028|PMID:25745997
Biological Process	GO:0030948	negative regulation of vascular endothelial growth factor receptor signaling pathway	MMRN2	IDA		Human	PMID:22020326
Biological Process	GO:1900426	positive regulation of defense response to bacterium	Mmrn2	IDA		Mouse	MGI:MGI:6810789|PMID:17988845
Biological Process	GO:1905278	positive regulation of epithelial tube formation	MMRN2	IDA		Human	PMID:25745997
Biological Process	GO:1905332	positive regulation of morphogenesis of an epithelium	MMRN2	IDA		Human	PMID:25745997

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern