Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MFSD2A
  • Mouse genes Mfsd2a
  • Rat genes Mfsd2a
  • Zfish genes mfsd2aa,mfsd2ab
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Mfsd2a

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0015245	fatty acid transmembrane transporter activity	Mfsd2a	IDA		Mouse	MGI:MGI:5571501|PMID:24828044
Molecular Function	GO:0005324	long-chain fatty acid transporter activity	MFSD2A	IMP		Human	PMID:26005865
Molecular Function	GO:0005324	long-chain fatty acid transporter activity	Mfsd2a	IMP		Mouse	MGI:MGI:5789479|PMID:27008858
Molecular Function	GO:0140348	lysophosphatidylcholine flippase activity	Mfsd2a	IDA		Mouse	MGI:MGI:6316418|PMID:26945070
Molecular Function	GO:0051978	lysophospholipid:sodium symporter activity	MFSD2A	IDA		Human	PMID:24828044
Molecular Function	GO:0051978	lysophospholipid:sodium symporter activity	MFSD2A	IDA		Human	PMID:34135507
Molecular Function	GO:0051978	lysophospholipid:sodium symporter activity	Mfsd2a	IDA		Mouse	MGI:MGI:6810698|PMID:34349262
Molecular Function	GO:0051978	lysophospholipid:sodium symporter activity	Mfsd2a	IDA		Mouse	MGI:MGI:5571501|PMID:24828044
Molecular Function	GO:1901480	oleate transmembrane transporter activity	MFSD2A	IMP		Human	PMID:26005865
Molecular Function	GO:0015293	symporter activity	Mfsd2a	IMP		Mouse	MGI:MGI:5571501|PMID:24828044
Cellular Component	GO:0005886	plasma membrane	MFSD2A	IDA		Human	PMID:26005865
Cellular Component	GO:0005886	plasma membrane	MFSD2A	IDA		Human	PMID:26005868
Cellular Component	GO:0005886	plasma membrane	Mfsd2a	IDA		Mouse	MGI:MGI:5474727|PMID:23209793
Cellular Component	GO:0005886	plasma membrane	Mfsd2a	IMP		Mouse	MGI:MGI:5571503|PMID:24828040
Biological Process	GO:0007420	brain development	MFSD2A	IMP		Human	PMID:26005865
Biological Process	GO:0007420	brain development	MFSD2A	IMP		Human	PMID:26005868
Biological Process	GO:0007420	brain development	Mfsd2a	IMP		Mouse	MGI:MGI:6196220|PMID:30074985
Biological Process	GO:0009267	cellular response to starvation	Mfsd2a	IMP		Mouse	MGI:MGI:5474727|PMID:23209793
Biological Process	GO:0050890	cognition	MFSD2A	IMP		Human	PMID:26005868
Biological Process	GO:0097009	energy homeostasis	Mfsd2a	IMP		Mouse	MGI:MGI:5474727|PMID:23209793
Biological Process	GO:0060856	establishment of blood-brain barrier	Mfsd2a	IMP		Mouse	MGI:MGI:5571503|PMID:24828040
Biological Process	GO:0015908	fatty acid transport	MFSD2A	IMP		Human	PMID:26005865
Biological Process	GO:0015908	fatty acid transport	Mfsd2a	IMP		Mouse	MGI:MGI:5571501|PMID:24828044
Biological Process	GO:0021766	hippocampus development	Mfsd2a	IDA		Mouse	MGI:MGI:5571501|PMID:24828044
Biological Process	GO:1990379	lipid transport across blood-brain barrier	MFSD2A	IMP		Human	PMID:26005865
Biological Process	GO:1990379	lipid transport across blood-brain barrier	Mfsd2a	IMP		Mouse	MGI:MGI:5571501|PMID:24828044
Biological Process	GO:0015909	long-chain fatty acid transport	Mfsd2a	IMP		Mouse	MGI:MGI:5789479|PMID:27008858
Biological Process	GO:0140329	lysophospholipid translocation	MFSD2A	IMP		Human	PMID:26005865
Biological Process	GO:0051977	lysophospholipid transport	MFSD2A	IDA		Human	PMID:24828044
Biological Process	GO:0051977	lysophospholipid transport	MFSD2A	IMP		Human	PMID:26005868
Biological Process	GO:0051977	lysophospholipid transport	Mfsd2a	IDA		Mouse	MGI:MGI:5571501|PMID:24828044
Biological Process	GO:0051977	lysophospholipid transport	Mfsd2a	IDA		Mouse	MGI:MGI:6810698|PMID:34349262
Biological Process	GO:0051977	lysophospholipid transport	Mfsd2a	IMP		Mouse	MGI:MGI:5774919|PMID:26005868
Biological Process	GO:0051977	lysophospholipid transport	mfsd2ab	IDA		Zfish	PMID:26005868
Biological Process	GO:0051977	lysophospholipid transport	mfsd2aa	IDA		Zfish	PMID:26005868
Biological Process	GO:0035633	maintenance of blood-brain barrier	Mfsd2a	IMP		Mouse	MGI:MGI:6196220|PMID:30074985
Biological Process	GO:0035633	maintenance of blood-brain barrier	mfsd2aa	IMP	ZFIN:ZDB-MRPHLNO-150928-7	Zfish	PMID:26005868
Biological Process	GO:0061744	motor behavior	Mfsd2a	IMP		Mouse	MGI:MGI:5474727|PMID:23209793
Biological Process	GO:0031999	negative regulation of fatty acid beta-oxidation	Mfsd2a	IMP		Mouse	MGI:MGI:5474727|PMID:23209793
Biological Process	GO:0008594	photoreceptor cell morphogenesis	Mfsd2a	IMP		Mouse	MGI:MGI:5789479|PMID:27008858
Biological Process	GO:0035845	photoreceptor cell outer segment organization	Mfsd2a	IMP		Mouse	MGI:MGI:5789479|PMID:27008858
Biological Process	GO:0030307	positive regulation of cell growth	Mfsd2a	IMP		Mouse	MGI:MGI:5474727|PMID:23209793
Biological Process	GO:0010867	positive regulation of triglyceride biosynthetic process	Mfsd2a	IMP		Mouse	MGI:MGI:5474727|PMID:23209793
Biological Process	GO:0050773	regulation of dendrite development	Mfsd2a	IMP		Mouse	MGI:MGI:6196220|PMID:30074985
Biological Process	GO:0040014	regulation of multicellular organism growth	Mfsd2a	IMP		Mouse	MGI:MGI:5474727|PMID:23209793
Biological Process	GO:0150011	regulation of neuron projection arborization	Mfsd2a	IMP		Mouse	MGI:MGI:6196220|PMID:30074985
Biological Process	GO:0150172	regulation of phosphatidylcholine metabolic process	MFSD2A	IMP		Human	PMID:26005868
Biological Process	GO:0150172	regulation of phosphatidylcholine metabolic process	Mfsd2a	IMP		Mouse	MGI:MGI:6196220|PMID:30074985
Biological Process	GO:0150175	regulation of phosphatidylethanolamine metabolic process	Mfsd2a	IMP		Mouse	MGI:MGI:6196220|PMID:30074985
Biological Process	GO:0150178	regulation of phosphatidylserine metabolic process	Mfsd2a	IMP		Mouse	MGI:MGI:6196220|PMID:30074985
Biological Process	GO:0060042	retina morphogenesis in camera-type eye	Mfsd2a	IMP		Mouse	MGI:MGI:5789479|PMID:27008858
Biological Process	GO:0003406	retinal pigment epithelium development	Mfsd2a	IMP		Mouse	MGI:MGI:5789479|PMID:27008858
Biological Process	GO:0045056	transcytosis	Mfsd2a	IMP		Mouse	MGI:MGI:5571503|PMID:24828040
Biological Process	GO:0034379	very-low-density lipoprotein particle assembly	Mfsd2a	IMP		Mouse	MGI:MGI:5474727|PMID:23209793

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern