Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes METTL16
  • Mouse genes Mettl16
  • Rat genes Mettl16
  • Zfish genes mettl16
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Mettl16

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0001734	mRNA (N6-adenosine)-methyltransferase activity	METTL16	IDA		Human	PMID:28525753
Molecular Function	GO:0001734	mRNA (N6-adenosine)-methyltransferase activity	METTL16	IDA		Human	PMID:30197297
Molecular Function	GO:0001734	mRNA (N6-adenosine)-methyltransferase activity	METTL16	IDA		Human	PMID:30197299
Molecular Function	GO:0001734	mRNA (N6-adenosine)-methyltransferase activity	METTL16	IDA		Human	PMID:33428944
Molecular Function	GO:0001734	mRNA (N6-adenosine)-methyltransferase activity	Mettl16	IDA		Mouse	MGI:MGI:6114846|PMID:29262316
Molecular Function	GO:0003723	RNA binding	METTL16	HDA		Human	PMID:22658674
Molecular Function	GO:0003723	RNA binding	METTL16	HDA		Human	PMID:22681889
Molecular Function	GO:0003723	RNA binding	METTL16	IDA		Human	PMID:27872311
Molecular Function	GO:0035613	RNA stem-loop binding	METTL16	IDA		Human	PMID:28525753
Molecular Function	GO:0120048	U6 snRNA (adenine-(43)-N(6))-methyltransferase activity	METTL16	IDA		Human	PMID:28525753
Molecular Function	GO:0120048	U6 snRNA (adenine-(43)-N(6))-methyltransferase activity	METTL16	IDA		Human	PMID:29051200
Molecular Function	GO:0120048	U6 snRNA (adenine-(43)-N(6))-methyltransferase activity	METTL16	IDA		Human	PMID:32266935
Molecular Function	GO:0030629	U6 snRNA 3'-end binding	METTL16	IDA		Human	PMID:28525753
Molecular Function	GO:0030629	U6 snRNA 3'-end binding	METTL16	IDA		Human	PMID:29051200
Cellular Component	GO:0005737	cytoplasm	METTL16	IDA		Human	PMID:31940410
Cellular Component	GO:0005634	nucleus	METTL16	IDA		Human	PMID:27872311
Cellular Component	GO:0005634	nucleus	METTL16	IDA		Human	PMID:31940410
Biological Process	GO:0006402	mRNA catabolic process	Mettl16	IDA		Mouse	MGI:MGI:6114846|PMID:29262316
Biological Process	GO:0061157	mRNA destabilization	Mettl16	IDA		Mouse	MGI:MGI:6114846|PMID:29262316
Biological Process	GO:0080009	mRNA methylation	METTL16	IDA		Human	PMID:30197297
Biological Process	GO:0080009	mRNA methylation	METTL16	IDA		Human	PMID:30197299
Biological Process	GO:0080009	mRNA methylation	METTL16	IDA		Human	PMID:33428944
Biological Process	GO:0080009	mRNA methylation	Mettl16	IMP		Mouse	MGI:MGI:6199095|PMID:30197299
Biological Process	GO:1905869	negative regulation of 3'-UTR-mediated mRNA stabilization	METTL16	IDA		Human	PMID:28525753
Biological Process	GO:0010608	post-transcriptional regulation of gene expression	METTL16	IDA		Human	PMID:28525753
Biological Process	GO:0010608	post-transcriptional regulation of gene expression	Mettl16	IDA		Mouse	MGI:MGI:6114846|PMID:29262316
Biological Process	GO:0048024	regulation of mRNA splicing, via spliceosome	METTL16	IDA		Human	PMID:28525753
Biological Process	GO:0001510	RNA methylation	Mettl16	IDA		Mouse	MGI:MGI:6114846|PMID:29262316
Biological Process	GO:0006556	S-adenosylmethionine biosynthetic process	METTL16	IDA		Human	PMID:28525753
Biological Process	GO:0006556	S-adenosylmethionine biosynthetic process	METTL16	IDA		Human	PMID:30197297
Biological Process	GO:0006556	S-adenosylmethionine biosynthetic process	METTL16	IMP		Human	PMID:30197299
Biological Process	GO:0006556	S-adenosylmethionine biosynthetic process	Mettl16	IMP		Mouse	MGI:MGI:6199095|PMID:30197299
Biological Process	GO:0120049	snRNA (adenine-N6)-methylation	METTL16	IDA		Human	PMID:28525753
Biological Process	GO:0120049	snRNA (adenine-N6)-methylation	METTL16	IDA		Human	PMID:29051200
Biological Process	GO:0120049	snRNA (adenine-N6)-methylation	METTL16	IDA		Human	PMID:32266935

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern