Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MEGF6
  • Mouse genes Megf6
  • Rat genes Megf6
  • Zfish genes megf6,megf6a,megf6b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Megf6

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	MEGF6	IPI	UniProtKB:O00555	Human	PMID:21078624
Molecular Function	GO:0005515	protein binding	MEGF6	IPI	UniProtKB:O15265	Human	PMID:21078624
Cellular Component	GO:0062023	collagen-containing extracellular matrix	Megf6	HDA		Mouse	MGI:MGI:6201853|PMID:28071719
Biological Process	GO:0035143	caudal fin morphogenesis	megf6a	IGI	ZFIN:ZDB-GENO-211028-6,ZFIN:ZDB-CRISPR-211022-2,ZFIN:ZDB-CRISPR-211022-3	Zfish	PMID:33026655
Biological Process	GO:0035143	caudal fin morphogenesis	megf6b	IGI	ZFIN:ZDB-GENO-211028-6,ZFIN:ZDB-CRISPR-211022-2,ZFIN:ZDB-CRISPR-211022-3	Zfish	PMID:33026655
Biological Process	GO:0043931	ossification involved in bone maturation	megf6b	IGI	ZFIN:ZDB-GENO-211028-6,ZFIN:ZDB-CRISPR-211022-2,ZFIN:ZDB-CRISPR-211022-3	Zfish	PMID:33026655
Biological Process	GO:0043931	ossification involved in bone maturation	megf6a	IGI	ZFIN:ZDB-GENO-211028-6,ZFIN:ZDB-CRISPR-211022-2,ZFIN:ZDB-CRISPR-211022-3	Zfish	PMID:33026655

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern