Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MED27
  • Mouse genes Med27
  • Rat genes Med27
  • Zfish genes med27
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Med27

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	MED27	IPI	UniProtKB:Q15528	Human	PMID:12584197
Molecular Function	GO:0005515	protein binding	MED27	IPI	UniProtKB:Q9CQI9	Human	PMID:12584197
Molecular Function	GO:0005515	protein binding	MED27	IPI	UniProtKB:O75586	Human	PMID:24882805
Molecular Function	GO:0005515	protein binding	MED27	IPI	UniProtKB:Q15528	Human	PMID:24882805
Molecular Function	GO:0005515	protein binding	MED27	IPI	UniProtKB:Q9CQI9	Human	PMID:24882805
Molecular Function	GO:0005515	protein binding	MED27	IPI	UniProtKB:Q9D7W5	Human	PMID:24882805
Molecular Function	GO:0005515	protein binding	MED27	IPI	UniProtKB:Q9NVC6	Human	PMID:24882805
Molecular Function	GO:0005515	protein binding	MED27	IPI	UniProtKB:Q9R0X0	Human	PMID:24882805
Molecular Function	GO:0005515	protein binding	MED27	IPI	UniProtKB:Q9NVC6	Human	PMID:24981860
Molecular Function	GO:0003713	transcription coactivator activity	MED27	IDA		Human	PMID:10882111
Molecular Function	GO:0003713	transcription coactivator activity	MED27	IDA		Human	PMID:9989412
Molecular Function	GO:0061630	ubiquitin protein ligase activity	Med27	IDA		Rat	PMID:12149480|RGD:2304264
Cellular Component	GO:0070847	core mediator complex	MED27	IPI		Human	PMID:24882805
Cellular Component	GO:0005829	cytosol	MED27	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005730	nucleolus	MED27	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	MED27	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	MED27	IDA		Human	PMID:24882805
Cellular Component	GO:0005634	nucleus	MED27	IDA		Human	PMID:9989412
Cellular Component	GO:0005667	transcription regulator complex	MED27	IDA		Human	PMID:9989412
Cellular Component	GO:0000151	ubiquitin ligase complex	Med27	IDA		Rat	PMID:12149480|RGD:2304264
Biological Process	GO:0043010	camera-type eye development	med27	IMP	ZFIN:ZDB-GENO-060308-2	Zfish	PMID:16582438
Biological Process	GO:0016567	protein ubiquitination	Med27	IDA		Rat	PMID:12149480|RGD:2304264
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	MED27	IDA		Human	PMID:9989412
Biological Process	GO:0046549	retinal cone cell development	med27	IMP	ZFIN:ZDB-GENO-060308-2	Zfish	PMID:16582438
Biological Process	GO:0035019	somatic stem cell population maintenance	Med27	IMP		Mouse	PMID:20720539

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern