Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MED23
  • Mouse genes Med23
  • Rat genes Med23
  • Zfish genes med23
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Med23

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	MED23	IPI	UniProtKB:P61201	Human	PMID:17438371
Molecular Function	GO:0005515	protein binding	MED23	IPI	UniProtKB:P28033	Human	PMID:20111005
Molecular Function	GO:0005515	protein binding	MED23	IPI	UniProtKB:O60244	Human	PMID:24882805
Molecular Function	GO:0005515	protein binding	MED23	IPI	UniProtKB:Q71SY5	Human	PMID:24882805
Molecular Function	GO:0005515	protein binding	MED23	IPI	UniProtKB:Q9Y2X0	Human	PMID:24882805
Molecular Function	GO:0005515	protein binding	MED23	IPI	UniProtKB:O60244	Human	PMID:25281560
Molecular Function	GO:0005515	protein binding	MED23	IPI	UniProtKB:Q71SY5	Human	PMID:25281560
Molecular Function	GO:0005515	protein binding	MED23	IPI	UniProtKB:Q9Y2X0	Human	PMID:25281560
Molecular Function	GO:0005515	protein binding	MED23	IPI	UniProtKB:Q71SY5	Human	PMID:25792360
Molecular Function	GO:0061630	ubiquitin protein ligase activity	Med23	IDA		Rat	PMID:12149480|RGD:2304264
Cellular Component	GO:0070847	core mediator complex	MED23	IPI		Human	PMID:24882805
Cellular Component	GO:0016592	mediator complex	Med23	IDA		Mouse	PMID:15340084
Cellular Component	GO:0005634	nucleus	MED23	IDA		Human	PMID:24882805
Cellular Component	GO:0005667	transcription regulator complex	MED23	IDA		Human	PMID:9989412
Cellular Component	GO:0000151	ubiquitin ligase complex	Med23	IDA		Rat	PMID:12149480|RGD:2304264
Biological Process	GO:0072359	circulatory system development	med23	IMP	ZFIN:ZDB-MRPHLNO-121128-2	Zfish	PMID:22972934
Biological Process	GO:0072359	circulatory system development	med23	IMP	ZFIN:ZDB-MRPHLNO-121128-1	Zfish	PMID:22972934
Biological Process	GO:0050768	negative regulation of neurogenesis	med23	IMP	ZFIN:ZDB-MRPHLNO-121128-1	Zfish	PMID:25564654
Biological Process	GO:0050768	negative regulation of neurogenesis	med23	IMP	ZFIN:ZDB-MRPHLNO-121128-2	Zfish	PMID:25564654
Biological Process	GO:0043473	pigmentation	med23	IMP	ZFIN:ZDB-MRPHLNO-121128-2	Zfish	PMID:28834744
Biological Process	GO:0043473	pigmentation	med23	IMP	ZFIN:ZDB-MRPHLNO-121128-1	Zfish	PMID:28834744
Biological Process	GO:0010628	positive regulation of gene expression	Med23	IMP	MGI:MGI:5568337	Mouse	PMID:25054639
Biological Process	GO:0010628	positive regulation of gene expression	Med23	IMP	MGI:MGI:3526093	Mouse	PMID:25054639
Biological Process	GO:2000409	positive regulation of T cell extravasation	Med23	IMP	MGI:MGI:3526093	Mouse	PMID:25054639
Biological Process	GO:2000409	positive regulation of T cell extravasation	Med23	IMP	MGI:MGI:5568337	Mouse	PMID:25054639
Biological Process	GO:0016567	protein ubiquitination	Med23	IDA		Rat	PMID:12149480|RGD:2304264
Biological Process	GO:0006355	regulation of DNA-templated transcription	MED23	IDA		Human	PMID:9989412

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern