Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MED10
  • Mouse genes Med10
  • Rat genes Med10
  • Zfish genes med10
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Med10

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	MED10	IPI	UniProtKB:O43513	Human	PMID:14576168
Molecular Function	GO:0005515	protein binding	MED10	IPI	UniProtKB:O43513	Human	PMID:15175163
Molecular Function	GO:0005515	protein binding	MED10	IPI	UniProtKB:O43513	Human	PMID:24882805
Molecular Function	GO:0005515	protein binding	MED10	IPI	UniProtKB:O43513	Human	PMID:24981860
Molecular Function	GO:0005515	protein binding	MED10	IPI	UniProtKB:O43513	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	MED10	IPI	UniProtKB:P04066	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MED10	IPI	UniProtKB:Q99819	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MED10	IPI	UniProtKB:Q9H8W5-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MED10	IPI	UniProtKB:Q9NYB9-2	Human	PMID:32296183
Molecular Function	GO:0061630	ubiquitin protein ligase activity	Med10	IDA		Rat	PMID:12149480|RGD:2304264
Cellular Component	GO:0070847	core mediator complex	MED10	IPI		Human	PMID:24882805
Cellular Component	GO:0016592	mediator complex	Med10	IDA		Mouse	PMID:15340084
Cellular Component	GO:0005654	nucleoplasm	MED10	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	MED10	IDA		Human	PMID:24882805
Cellular Component	GO:0000151	ubiquitin ligase complex	Med10	IDA		Rat	PMID:12149480|RGD:2304264
Biological Process	GO:0036302	atrioventricular canal development	med10	IMP	ZFIN:ZDB-MRPHLNO-070628-1	Zfish	PMID:27343557
Biological Process	GO:0036302	atrioventricular canal development	med10	IGI	ZFIN:ZDB-GENE-990726-27,ZFIN:ZDB-GENO-161014-2	Zfish	PMID:27343557
Biological Process	GO:0036302	atrioventricular canal development	med10	IMP	ZFIN:ZDB-MRPHLNO-161005-2	Zfish	PMID:27343557
Biological Process	GO:0036302	atrioventricular canal development	med10	IGI	ZFIN:ZDB-GENO-161014-11,ZFIN:ZDB-MRPHLNO-161005-3	Zfish	PMID:27343557
Biological Process	GO:0036302	atrioventricular canal development	med10	IMP	ZFIN:ZDB-GENO-161014-2	Zfish	PMID:27343557
Biological Process	GO:1905072	cardiac jelly development	med10	IMP	ZFIN:ZDB-GENO-161014-5	Zfish	PMID:27343557
Biological Process	GO:0007507	heart development	med10	IMP	ZFIN:ZDB-GENO-980202-434	Zfish	PMID:17208216
Biological Process	GO:0007507	heart development	med10	IMP	ZFIN:ZDB-MRPHLNO-070628-1	Zfish	PMID:17208216
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Med10	IDA		Mouse	PMID:15340084
Biological Process	GO:0016567	protein ubiquitination	Med10	IDA		Rat	PMID:12149480|RGD:2304264
Biological Process	GO:0035019	somatic stem cell population maintenance	Med10	IMP		Mouse	PMID:20720539

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern