Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MEAK7
  • Mouse genes Meak7
  • Rat genes Meak7
  • Zfish genes meak7
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Meak7

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	MEAK7	IPI	UniProtKB:Q15645	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	MEAK7	IPI	UniProtKB:Q15645	Human	PMID:19060904
Molecular Function	GO:0005515	protein binding	MEAK7	IPI	UniProtKB:P42345|UniProtKB:Q9BVC4	Human	PMID:29750193
Molecular Function	GO:0005515	protein binding	MEAK7	IPI	UniProtKB:Q15645	Human	PMID:31515488
Cellular Component	GO:0005737	cytoplasm	MEAK7	IDA		Human	PMID:24223779
Cellular Component	GO:0005829	cytosol	MEAK7	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005765	lysosomal membrane	MEAK7	HDA		Human	PMID:17897319
Cellular Component	GO:0005765	lysosomal membrane	MEAK7	IDA		Human	PMID:29750193
Cellular Component	GO:0016020	membrane	MEAK7	IDA		Human	PMID:24223779
Cellular Component	GO:0005730	nucleolus	MEAK7	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	MEAK7	IDA		Human	GO_REF:0000052
Biological Process	GO:1900408	negative regulation of cellular response to oxidative stress	Meak7	IDA		Mouse	PMID:26668325
Biological Process	GO:0150032	positive regulation of protein localization to lysosome	MEAK7	IDA		Human	PMID:29750193
Biological Process	GO:0030334	regulation of cell migration	MEAK7	IDA		Human	PMID:29750193
Biological Process	GO:0042127	regulation of cell population proliferation	MEAK7	IDA		Human	PMID:29750193
Biological Process	GO:0043200	response to amino acid	MEAK7	IDA		Human	PMID:29750193
Biological Process	GO:0032868	response to insulin	MEAK7	IDA		Human	PMID:29750193
Biological Process	GO:0031667	response to nutrient levels	MEAK7	IDA		Human	PMID:29750193
Biological Process	GO:0031929	TOR signaling	MEAK7	IMP		Human	PMID:29750193

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern