Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MDM1
  • Mouse genes Mdm1
  • Rat genes Mdm1
  • Zfish genes mdm1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Mdm1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0008017	microtubule binding	MDM1	IMP		Human	PMID:26337392
Molecular Function	GO:0005515	protein binding	MDM1	IPI	UniProtKB:Q2TAC2-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MDM1	IPI	UniProtKB:Q9NSC5	Human	PMID:32296183
Cellular Component	GO:0034451	centriolar satellite	MDM1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005814	centriole	MDM1	IDA		Human	PMID:26337392
Cellular Component	GO:0005814	centriole	Mdm1	IDA		Mouse	MGI:MGI:5707092|PMID:26337392
Cellular Component	GO:0005813	centrosome	MDM1	IDA		Human	PMID:26337392
Cellular Component	GO:0005813	centrosome	Mdm1	IDA		Mouse	PMID:23300604
Cellular Component	GO:0005829	cytosol	MDM1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0097730	non-motile cilium	Mdm1	IDA		Mouse	PMID:23300604
Cellular Component	GO:0005634	nucleus	MDM1	IDA		Human	PMID:26337392
Biological Process	GO:0046600	negative regulation of centriole replication	MDM1	IMP		Human	PMID:26337392
Biological Process	GO:0060041	retina development in camera-type eye	Mdm1	IMP	MGI:MGI:2664154	Mouse	PMID:21052544

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern