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Mdm1
Gene Detail
Symbol

Name
ID
Mdm1
transformed mouse 3T3 cell double minute 1
MGI:96951
Synonyms
Arrd2, Mdm-1
Feature Type
protein coding gene
Genetic Map
Chromosome 10
66.65 cM, cytoband C1-C3
Detailed Genetic Map ± 1 cM


Mapping data(28)
Sequence Map
Chr10:118141787-118168997 bp, + strand
From Ensembl annotation of GRCm38

  27211 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:9692  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Mdm1

Human
homologs
Human Homolog MDM1, Mdm1 nuclear protein homolog (mouse)
NCBI Gene ID 56890
neXtProt AC  NX_Q8TC05
Human Chr (Location)  12q15; chr12:68294566-68332381 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(4) : QTL(2) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a nonsense point mutation exhibit retinal degeneration, abnormal eye electrophysiology.
 
Interactions
Mdm1 interacts with 193 markers (Mir1b, Mir7-1, Mir7-2, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (3 annotations)
Process retina development in camera-type eye
Component nucleus
External Resources: FuncBase
Expression
Literature Summary: (1 records)
Data Summary: Results (7)    Tissues (4)    Images (5)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 7
cDNA source data(14)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(19) Genomic(4) cDNA(15)
Microarray probesets(4)
Other database
links
Ensembl Gene ModelENSMUSG00000020212 (Evidence)
Entrez Gene17245 (Evidence)
DFCITC1579144, TC1592395, TC1676850, TC1715548, TC1781194
DoTSDT.103564187, DT.40159021, DT.490336
NIA Mouse Gene IndexU012053
Consensus CDS ProjectCCDS36069.1, CCDS48697.1, CCDS48698.1, CCDS48699.1
International Mouse Knockout Project StatusMdm1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000020212 Ensembl Gene Model | MGI Sequence Detail 27211 C57BL/6J ±  kb
transcript ENSMUST00000163238 Ensembl | MGI Sequence Detail 3149 Not Applicable 
polypeptide ENSMUSP00000127919 Ensembl | MGI Sequence Detail 718 Not Applicable 

For the selected sequences
All sequences(66) RefSeq(18) UniProt(13)
Polymorphisms
RFLP(5) : SNPs within 2kb(282 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
Protein Ontology PR:000010266 nuclear protein MDM1
References
(Earliest) J:8787 Cahilly-Snyder L, et al., Molecular analysis and chromosomal mapping of amplified genes isolated from a transformed mouse 3T3 cell line. Somat Cell Mol Genet. 1987 May;13(3):235-44
(Latest) J:166679 Won J, et al., Mouse model resources for vision research. J Ophthalmol. 2011;2011:391384
All references(41)
Other
accession IDs
MGD-MRK-12168, MGD-MRK-12171, MGI:2664138

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory