Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MCUB
  • Mouse genes Mcub
  • Rat genes Mcub
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Mcub

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0019855	calcium channel inhibitor activity	Mcub	IDA		Mouse	MGI:MGI:5514486|PMID:23900286
Molecular Function	GO:0005515	protein binding	Mcub	IPI	UniProtKB:Q3UMR5	Mouse	MGI:MGI:5514486|PMID:23900286
Cellular Component	GO:0034704	calcium channel complex	Mcub	IDA		Mouse	MGI:MGI:5514486|PMID:23900286
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	MCUB	IDA		Human	GO_REF:0000052
Cellular Component	GO:0016020	membrane	Mcub	IDA		Mouse	MGI:MGI:5514486|PMID:23900286
Cellular Component	GO:0005743	mitochondrial inner membrane	MCUB	IDA		Human	PMID:24231807
Cellular Component	GO:0005739	mitochondrion	MCUB	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005739	mitochondrion	Mcub	IMP		Mouse	MGI:MGI:5514486|PMID:23900286
Cellular Component	GO:0005654	nucleoplasm	MCUB	IDA		Human	GO_REF:0000052
Cellular Component	GO:1990246	uniplex complex	MCUB	IDA		Human	PMID:24231807
Biological Process	GO:0051560	mitochondrial calcium ion homeostasis	Mcub	IMP		Mouse	MGI:MGI:5514486|PMID:23900286
Biological Process	GO:0006851	mitochondrial calcium ion transmembrane transport	Mcub	IMP		Mouse	MGI:MGI:5514486|PMID:23900286

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern