Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MCM7
  • Mouse genes Mcm7
  • Rat genes Mcm7
  • Zfish genes mcm7
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Mcm7

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003678	DNA helicase activity	MCM7	IDA		Human	PMID:25661590
Molecular Function	GO:0003678	DNA helicase activity	MCM7	IDA		Human	PMID:9305914
Molecular Function	GO:0003678	DNA helicase activity	Mcm7	IMP		Mouse	MGI:MGI:2429455|PMID:12207017
Molecular Function	GO:0003678	DNA helicase activity	Mcm7	IDA		Mouse	PMID:15917436
Molecular Function	GO:0005515	protein binding	MCM7	IPI	UniProtKB:P09884	Human	PMID:10518787
Molecular Function	GO:0005515	protein binding	MCM7	IPI	UniProtKB:P33991	Human	PMID:12364596
Molecular Function	GO:0005515	protein binding	MCM7	IPI	UniProtKB:P33991	Human	PMID:15232106
Molecular Function	GO:0005515	protein binding	MCM7	IPI	UniProtKB:P33992	Human	PMID:15232106
Molecular Function	GO:0005515	protein binding	MCM7	IPI	UniProtKB:P49736	Human	PMID:15232106
Molecular Function	GO:0005515	protein binding	MCM7	IPI	UniProtKB:O75943	Human	PMID:15538388
Molecular Function	GO:0005515	protein binding	MCM7	IPI	UniProtKB:P53350	Human	PMID:15654075
Molecular Function	GO:0005515	protein binding	MCM7	IPI	UniProtKB:P46527	Human	PMID:16289477
Molecular Function	GO:0005515	protein binding	MCM7	IPI	UniProtKB:P49918	Human	PMID:16289477
Molecular Function	GO:0005515	protein binding	MCM7	IPI	UniProtKB:Q14566	Human	PMID:16438930
Molecular Function	GO:0005515	protein binding	MCM7	IPI	UniProtKB:Q14683	Human	PMID:16438930
Molecular Function	GO:0005515	protein binding	MCM7	IPI	UniProtKB:P49736	Human	PMID:16899510
Molecular Function	GO:0005515	protein binding	MCM7	IPI	UniProtKB:Q08945	Human	PMID:16902406
Molecular Function	GO:0005515	protein binding	MCM7	IPI	UniProtKB:P33991	Human	PMID:17296731
Molecular Function	GO:0005515	protein binding	MCM7	IPI	UniProtKB:P49736	Human	PMID:17296731
Molecular Function	GO:0005515	protein binding	MCM7	IPI	UniProtKB:Q14566	Human	PMID:17296731
Molecular Function	GO:0005515	protein binding	MCM7	IPI	UniProtKB:Q9BTE3	Human	PMID:17296731
Molecular Function	GO:0005515	protein binding	MCM7	IPI	UniProtKB:P0CG47	Human	PMID:17310990
Molecular Function	GO:0005515	protein binding	MCM7	IPI	UniProtKB:Q9UL03	Human	PMID:17310990
Molecular Function	GO:0005515	protein binding	MCM7	IPI	UniProtKB:P01106	Human	PMID:17314511
Molecular Function	GO:0005515	protein binding	MCM7	IPI	UniProtKB:O75179	Human	PMID:19150984
Molecular Function	GO:0005515	protein binding	MCM7	IPI	UniProtKB:P33991	Human	PMID:22540012
Molecular Function	GO:0005515	protein binding	MCM7	IPI	UniProtKB:P49736	Human	PMID:22540012
Molecular Function	GO:0005515	protein binding	MCM7	IPI	UniProtKB:Q9BTE3	Human	PMID:22540012
Molecular Function	GO:0005515	protein binding	MCM7	IPI	UniProtKB:P07948	Human	PMID:23764002
Molecular Function	GO:0005515	protein binding	MCM7	IPI	UniProtKB:P07948-1	Human	PMID:23764002
Molecular Function	GO:0005515	protein binding	MCM7	IPI	UniProtKB:P33991	Human	PMID:23764002
Molecular Function	GO:0005515	protein binding	MCM7	IPI	UniProtKB:P33992	Human	PMID:23764002
Molecular Function	GO:0005515	protein binding	MCM7	IPI	UniProtKB:P49736	Human	PMID:23764002
Molecular Function	GO:0005515	protein binding	MCM7	IPI	UniProtKB:Q14566	Human	PMID:23764002
Molecular Function	GO:0005515	protein binding	MCM7	IPI	UniProtKB:P33991	Human	PMID:24299456
Molecular Function	GO:0005515	protein binding	MCM7	IPI	UniProtKB:Q9BTE3	Human	PMID:24299456
Molecular Function	GO:0005515	protein binding	MCM7	IPI	UniProtKB:Q9BTE3	Human	PMID:25036637
Molecular Function	GO:0005515	protein binding	MCM7	IPI	UniProtKB:P14373	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	MCM7	IPI	UniProtKB:Q02086	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	MCM7	IPI	UniProtKB:Q08379	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	MCM7	IPI	UniProtKB:Q15742	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	MCM7	IPI	UniProtKB:Q68D86	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	MCM7	IPI	UniProtKB:Q8N6Y0	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	MCM7	IPI	UniProtKB:Q8ND90	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	MCM7	IPI	UniProtKB:Q8TD10	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	MCM7	IPI	UniProtKB:Q96MA6	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	MCM7	IPI	UniProtKB:Q9BTE3	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	MCM7	IPI	UniProtKB:Q9BVG8	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	MCM7	IPI	UniProtKB:Q9BYV2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	MCM7	IPI	UniProtKB:Q9NS73-5	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	MCM7	IPI	UniProtKB:Q9UMX0-2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	MCM7	IPI	UniProtKB:Q14566	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	MCM7	IPI	UniProtKB:Q9BTE3-2	Human	PMID:26871637
Molecular Function	GO:0005515	protein binding	MCM7	IPI	UniProtKB:P12004,UniProtKB:P49736,UniProtKB:Q7Z2Z1,UniProtKB:Q9NYP3	Human	PMID:28191891
Molecular Function	GO:0005515	protein binding	MCM7	IPI	UniProtKB:Q08945	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	MCM7	IPI	UniProtKB:Q96MA6	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	MCM7	IPI	UniProtKB:Q9BTE3-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MCM7	IPI	UniProtKB:P03126	Human	PMID:9705868
Molecular Function	GO:0005515	protein binding	MCM7	IPI	UniProtKB:P06462	Human	PMID:9705868
Molecular Function	GO:0005515	protein binding	MCM7	IPI	UniProtKB:P06463	Human	PMID:9705868
Molecular Function	GO:0005515	protein binding	Mcm7	IPI	UniProtKB:P46414	Mouse	MGI:MGI:5508261|PMID:16289477
Molecular Function	GO:0005515	protein binding	Mcm7	IPI	PR:P97311	Mouse	PMID:15917436
Molecular Function	GO:0005515	protein binding	Mcm7	IPI	PR:P49717	Mouse	PMID:15917436
Molecular Function	GO:0003697	single-stranded DNA binding	MCM7	IDA		Human	PMID:25661590
Molecular Function	GO:0003697	single-stranded DNA binding	Mcm7	IMP		Mouse	MGI:MGI:2429455|PMID:12207017
Molecular Function	GO:0003697	single-stranded DNA binding	Mcm7	IPI	PR:P49717	Mouse	PMID:15917436
Molecular Function	GO:0003697	single-stranded DNA binding	Mcm7	IPI	PR:P97311	Mouse	PMID:15917436
Cellular Component	GO:0000781	chromosome, telomeric region	MCM7	HDA		Human	PMID:19135898
Cellular Component	GO:0071162	CMG complex	MCM7	IPI		Human	PMID:22474384
Cellular Component	GO:0005829	cytosol	MCM7	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005829	cytosol	Mcm7	IDA		Rat	PMID:19821535|RGD:2316313
Cellular Component	GO:0042555	MCM complex	MCM7	IPI		Human	PMID:22540012
Cellular Component	GO:0042555	MCM complex	MCM7	IMP		Human	PMID:15538388
Cellular Component	GO:0042555	MCM complex	MCM7	IDA		Human	PMID:17296731
Cellular Component	GO:0042555	MCM complex	MCM7	IDA		Human	PMID:25661590
Cellular Component	GO:0042555	MCM complex	Mcm7	IDA		Mouse	MGI:MGI:2429455|PMID:12207017
Cellular Component	GO:0042555	MCM complex	Mcm7	IDA		Mouse	MGI:MGI:1353541|PMID:10567526
Cellular Component	GO:0016020	membrane	MCM7	HDA		Human	PMID:19946888
Cellular Component	GO:0005654	nucleoplasm	MCM7	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	MCM7	IDA		Human	PMID:21383955
Cellular Component	GO:0005634	nucleus	MCM7	IDA		Human	PMID:22474384
Cellular Component	GO:0005634	nucleus	Mcm7	IDA		Mouse	PMID:12972605
Cellular Component	GO:0005634	nucleus	Mcm7	IDA		Rat	PMID:12677008|RGD:1304505
Biological Process	GO:0008283	cell population proliferation	Mcm7	IDA		Mouse	PMID:12972605
Biological Process	GO:0071364	cellular response to epidermal growth factor stimulus	Mcm7	IEP		Rat	PMID:19821535|RGD:2316313
Biological Process	GO:0071310	cellular response to organic substance	Mcm7	IEP		Rat	PMID:12591091|RGD:2317700
Biological Process	GO:0071466	cellular response to xenobiotic stimulus	Mcm7	IDA		Mouse	PMID:24726645
Biological Process	GO:0006974	DNA damage response	MCM7	IMP		Human	PMID:15538388
Biological Process	GO:0006268	DNA unwinding involved in DNA replication	MCM7	IDA		Human	PMID:22474384
Biological Process	GO:0006268	DNA unwinding involved in DNA replication	Mcm7	IPI	PR:P49717	Mouse	PMID:15917436
Biological Process	GO:0006268	DNA unwinding involved in DNA replication	Mcm7	IPI	PR:P97311	Mouse	PMID:15917436
Biological Process	GO:1902017	regulation of cilium assembly	mcm7	IMP	ZFIN:ZDB-MRPHLNO-190530-4	Zfish	PMID:30329080
Biological Process	GO:0042325	regulation of phosphorylation	MCM7	IMP		Human	PMID:15538388
Biological Process	GO:0009410	response to xenobiotic stimulus	Mcm7	IEP		Rat	PMID:12591091|RGD:2317700

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern