Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MCAM
  • Mouse genes Mcam
  • Rat genes Mcam
  • Zfish genes mcama,mcamb
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Mcam

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Cellular Component	GO:0009897	external side of plasma membrane	MCAM	IDA		Human	PMID:20354148
Cellular Component	GO:0005576	extracellular region	MCAM	HDA		Human	PMID:27068509
Cellular Component	GO:0005615	extracellular space	Mcam	IDA		Rat	PMID:23649916|RGD:7364780
Cellular Component	GO:0005925	focal adhesion	MCAM	HDA		Human	PMID:21423176
Cellular Component	GO:0005634	nucleus	Mcam	IDA		Rat	PMID:23649916|RGD:7364780
Biological Process	GO:0001525	angiogenesis	MCAM	IDA		Human	PMID:23878390
Biological Process	GO:0001525	angiogenesis	mcamb	IMP	ZFIN:ZDB-MRPHLNO-101216-2	Zfish	PMID:20977546
Biological Process	GO:0031103	axon regeneration	mcamb	IMP	ZFIN:ZDB-MRPHLNO-161205-1	Zfish	PMID:27318029
Biological Process	GO:0001568	blood vessel development	mcamb	IMP	ZFIN:ZDB-MRPHLNO-050209-4	Zfish	PMID:15580611
Biological Process	GO:0001568	blood vessel development	mcamb	IMP	ZFIN:ZDB-MRPHLNO-050209-3	Zfish	PMID:15580611
Biological Process	GO:0060271	cilium assembly	mcamb	IMP	ZFIN:ZDB-MRPHLNO-101216-2	Zfish	PMID:28589943
Biological Process	GO:0060026	convergent extension	mcamb	IMP	ZFIN:ZDB-MRPHLNO-101216-2	Zfish	PMID:24335906
Biological Process	GO:0007368	determination of left/right symmetry	mcamb	IMP	ZFIN:ZDB-MRPHLNO-101216-2	Zfish	PMID:28589943
Biological Process	GO:0060287	epithelial cilium movement involved in determination of left/right asymmetry	mcamb	IMP	ZFIN:ZDB-MRPHLNO-101216-2	Zfish	PMID:28589943
Biological Process	GO:0003094	glomerular filtration	MCAM	IEP		Human	PMID:20354148
Biological Process	GO:0001946	lymphangiogenesis	mcamb	IMP	ZFIN:ZDB-MRPHLNO-101216-2	Zfish	PMID:28785085
Biological Process	GO:0030335	positive regulation of cell migration	Mcam	IDA		Rat	PMID:21042736|RGD:7364786
Biological Process	GO:0061042	vascular wound healing	MCAM	IEP		Human	PMID:20354148
Biological Process	GO:0001944	vasculature development	mcamb	IMP	ZFIN:ZDB-MRPHLNO-101216-2	Zfish	PMID:25656845

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern