Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MASP2
  • Mouse genes Masp2
  • Rat genes Masp2
  • Zfish genes masp2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Masp2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0048306	calcium-dependent protein binding	MASP2	IPI	UniProtKB:P11226	Human	PMID:12421953
Molecular Function	GO:0048306	calcium-dependent protein binding	MASP2	IPI	UniProtKB:Q15485	Human	PMID:12421953
Molecular Function	GO:0001855	complement component C4b binding	MASP2	IDA		Human	PMID:22949645
Molecular Function	GO:0008233	peptidase activity	MASP2	IDA		Human	PMID:10946292
Molecular Function	GO:0008233	peptidase activity	MASP2	IDA		Human	PMID:12538697
Molecular Function	GO:0008233	peptidase activity	Masp2	IDA		Rat	PMID:15060079|RGD:1600552
Molecular Function	GO:0005515	protein binding	MASP2	IPI	UniProtKB:P05155	Human	PMID:10946292
Molecular Function	GO:0005515	protein binding	MASP2	IPI	UniProtKB:P11226	Human	PMID:11290788
Molecular Function	GO:0005515	protein binding	MASP2	IPI	UniProtKB:O75636	Human	PMID:11907111
Molecular Function	GO:0005515	protein binding	MASP2	IPI	UniProtKB:P0C0L5:PRO_0000042699	Human	PMID:22071314
Molecular Function	GO:0005515	protein binding	MASP2	IPI	UniProtKB:Q9BWP8	Human	PMID:24174618
Molecular Function	GO:0005515	protein binding	MASP2	IPI	UniProtKB:P05155	Human	PMID:25359215
Molecular Function	GO:0005515	protein binding	MASP2	IPI	UniProtKB:P11226	Human	PMID:27104295
Molecular Function	GO:0005515	protein binding	MASP2	IPI	UniProtKB:P05155	Human	PMID:28742139
Molecular Function	GO:0005515	protein binding	Masp2	IPI	RGD:2231	Rat	PMID:15060079|RGD:1600552
Molecular Function	GO:0005515	protein binding	Masp2	IPI	RGD:3055	Rat	PMID:20118239|RGD:7242176
Molecular Function	GO:0005515	protein binding	Masp2	IPI	RGD:3665	Rat	PMID:20118239|RGD:7242176
Molecular Function	GO:0005515	protein binding	Masp2	IPI	RGD:67380	Rat	PMID:20118239|RGD:7242176
Molecular Function	GO:0004252	serine-type endopeptidase activity	MASP2	IDA		Human	PMID:9087411
Molecular Function	GO:0004252	serine-type endopeptidase activity	Masp2	IDA		Rat	PMID:15060079|RGD:1600552
Cellular Component	GO:0070062	extracellular exosome	MASP2	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	MASP2	HDA		Human	PMID:23533145
Biological Process	GO:0001867	complement activation, lectin pathway	MASP2	IDA		Human	PMID:17182967
Biological Process	GO:0001867	complement activation, lectin pathway	MASP2	IDA		Human	PMID:9087411

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern