Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MAPK12
  • Mouse genes Mapk12
  • Rat genes Mapk12
  • Zfish genes mapk12a,mapk12b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Mapk12

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005524	ATP binding	Mapk12	IDA		Rat	PMID:16879317|RGD:2298806
Molecular Function	GO:0000287	magnesium ion binding	MAPK12	IDA		Human	PMID:10508788
Molecular Function	GO:0004707	MAP kinase activity	Mapk12	IDA		Rat	PMID:16879317|RGD:2298806
Molecular Function	GO:0005515	protein binding	MAPK12	IPI	UniProtKB:Q16512	Human	PMID:12761180
Molecular Function	GO:0005515	protein binding	MAPK12	IPI	UniProtKB:Q91Y80	Human	PMID:15158451
Molecular Function	GO:0005515	protein binding	MAPK12	IPI	UniProtKB:P30793	Human	PMID:19294699
Molecular Function	GO:0005515	protein binding	MAPK12	IPI	UniProtKB:Q14160	Human	PMID:24550280
Molecular Function	GO:0005515	protein binding	MAPK12	IPI	UniProtKB:P29074	Human	PMID:25158884
Molecular Function	GO:0005515	protein binding	MAPK12	IPI	UniProtKB:Q12959	Human	PMID:25241761
Molecular Function	GO:0005515	protein binding	MAPK12	IPI	UniProtKB:Q8IUQ4	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	MAPK12	IPI	UniProtKB:Q12959	Human	PMID:30126976
Molecular Function	GO:0005515	protein binding	MAPK12	IPI	UniProtKB:Q14160	Human	PMID:30126976
Molecular Function	GO:0005515	protein binding	MAPK12	IPI	UniProtKB:P05067	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Mapk12	IPI	UniProtKB:Q13424	Rat	PMID:10212242|RGD:8554048
Molecular Function	GO:0005515	protein binding	Mapk12	IPI	RGD:68424	Rat	PMID:14741046|RGD:1358688
Molecular Function	GO:0004674	protein serine/threonine kinase activity	MAPK12	IDA		Human	PMID:15850461
Molecular Function	GO:0004674	protein serine/threonine kinase activity	MAPK12	IDA		Human	PMID:8633070
Molecular Function	GO:0004674	protein serine/threonine kinase activity	Mapk12	IDA		Rat	PMID:10438538|RGD:8553435
Cellular Component	GO:0005737	cytoplasm	Mapk12	IDA		Rat	PMID:11991731|RGD:729104
Biological Process	GO:0045445	myoblast differentiation	MAPK12	IDA		Human	PMID:8633070
Biological Process	GO:0045786	negative regulation of cell cycle	Mapk12	IDA		Rat	PMID:10438538|RGD:8553435
Biological Process	GO:0018105	peptidyl-serine phosphorylation	MAPK12	IDA		Human	PMID:15850461
Biological Process	GO:0006468	protein phosphorylation	Mapk12	IDA		Rat	PMID:16879317|RGD:2298806

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern