Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MAP3K2
  • Mouse genes Map3k2
  • Rat genes Map3k2
  • Zfish genes map3k2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Map3k2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004709	MAP kinase kinase kinase activity	Map3k2	IDA		Rat	PMID:10648842|RGD:2298801
Molecular Function	GO:0005515	protein binding	MAP3K2	IPI	UniProtKB:P31947	Human	PMID:15778465
Molecular Function	GO:0005515	protein binding	MAP3K2	IPI	UniProtKB:Q9UNE7	Human	PMID:20588253
Molecular Function	GO:0005515	protein binding	MAP3K2	IPI	UniProtKB:Q13163	Human	PMID:21988832
Molecular Function	GO:0005515	protein binding	MAP3K2	IPI	UniProtKB:P31947	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	MAP3K2	IPI	UniProtKB:Q9H7B4-1	Human	PMID:27066749
Molecular Function	GO:0005515	protein binding	MAP3K2	IPI	UniProtKB:Q13163	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	MAP3K2	IPI	UniProtKB:Q13163	Human	PMID:31980649
Molecular Function	GO:0005515	protein binding	MAP3K2	IPI	UniProtKB:Q13163	Human	PMID:32707033
Molecular Function	GO:0005515	protein binding	Map3k2	IPI	UniProtKB:Q9WVS7	Mouse	MGI:MGI:2675918|PMID:12912994
Molecular Function	GO:0004672	protein kinase activity	MAP3K2	IDA		Human	PMID:15001576
Molecular Function	GO:0019901	protein kinase binding	MAP3K2	IPI	UniProtKB:Q15208	Human	PMID:17906693
Cellular Component	GO:0005829	cytosol	MAP3K2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005829	cytosol	Map3k2	IDA		Rat	PMID:15075238|RGD:1582267
Cellular Component	GO:0005654	nucleoplasm	MAP3K2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	Map3k2	IDA		Rat	PMID:15075238|RGD:1582267
Biological Process	GO:0071260	cellular response to mechanical stimulus	MAP3K2	IEP		Human	PMID:19593445
Biological Process	GO:0035556	intracellular signal transduction	MAP3K2	IDA		Human	PMID:14515274
Biological Process	GO:0006468	protein phosphorylation	Map3k2	IDA		Rat	PMID:10648842|RGD:2298801

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern