Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes LZTR1
  • Mouse genes Lztr1
  • Rat genes Lztr1
  • Zfish genes lztr1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Lztr1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	LZTR1	IPI	UniProtKB:Q9UGJ1	Human	PMID:19060904
Molecular Function	GO:0005515	protein binding	LZTR1	IPI	UniProtKB:Q9UGJ1	Human	PMID:29892012
Molecular Function	GO:0005515	protein binding	LZTR1	IPI	UniProtKB:P60520	Human	PMID:32296183
Molecular Function	GO:0031267	small GTPase binding	LZTR1	IDA		Human	PMID:30442762
Molecular Function	GO:0031267	small GTPase binding	LZTR1	IDA		Human	PMID:30442766
Cellular Component	GO:0031463	Cul3-RING ubiquitin ligase complex	LZTR1	IDA		Human	PMID:30442762
Cellular Component	GO:0031463	Cul3-RING ubiquitin ligase complex	LZTR1	IDA		Human	PMID:30442766
Cellular Component	GO:0012505	endomembrane system	LZTR1	IDA		Human	PMID:30442762
Cellular Component	GO:0012505	endomembrane system	LZTR1	IDA		Human	PMID:30442766
Cellular Component	GO:0005794	Golgi apparatus	LZTR1	IDA		Human	PMID:16356934
Cellular Component	GO:0055038	recycling endosome membrane	LZTR1	IDA		Human	PMID:30442762
Biological Process	GO:0046580	negative regulation of Ras protein signal transduction	LZTR1	IDA		Human	PMID:30442762
Biological Process	GO:0046580	negative regulation of Ras protein signal transduction	LZTR1	IDA		Human	PMID:30442766
Biological Process	GO:0046580	negative regulation of Ras protein signal transduction	Lztr1	IMP		Mouse	MGI:MGI:6270047|PMID:30442762
Biological Process	GO:0016567	protein ubiquitination	LZTR1	IDA		Human	PMID:30442762
Biological Process	GO:0016567	protein ubiquitination	LZTR1	IDA		Human	PMID:30442766
Biological Process	GO:0016567	protein ubiquitination	Lztr1	IMP		Mouse	MGI:MGI:6270047|PMID:30442762

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern