Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes LY6E
  • Mouse genes Ly6e
  • Rat genes Ly6e
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ly6e

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0033130	acetylcholine receptor binding	Ly6e	IDA		Mouse	PMID:26276394
Molecular Function	GO:0030550	acetylcholine receptor inhibitor activity	Ly6e	IDA		Mouse	PMID:26276394
Molecular Function	GO:0005515	protein binding	LY6E	IPI	UniProtKB:A5PKU2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LY6E	IPI	UniProtKB:Q6ZSS7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LY6E	IPI	UniProtKB:Q96HH6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LY6E	IPI	UniProtKB:Q9NV12	Human	PMID:32296183
Biological Process	GO:0095500	acetylcholine receptor signaling pathway	Ly6e	IDA		Mouse	PMID:26276394
Biological Process	GO:0030325	adrenal gland development	Ly6e	IMP	MGI:MGI:2429638	Mouse	PMID:11784869
Biological Process	GO:0048242	epinephrine secretion	Ly6e	IMP	MGI:MGI:2429638	Mouse	PMID:11784869
Biological Process	GO:0001701	in utero embryonic development	Ly6e	IMP	MGI:MGI:2429638	Mouse	PMID:11784869
Biological Process	GO:0046597	negative regulation of viral entry into host cell	LY6E	IDA		Human	PMID:32641482
Biological Process	GO:0046597	negative regulation of viral entry into host cell	LY6E	IDA		Human	PMID:32704094
Biological Process	GO:0046597	negative regulation of viral entry into host cell	Ly6e	IMP		Mouse	MGI:MGI:6448667|PMID:32704094
Biological Process	GO:0042415	norepinephrine metabolic process	Ly6e	IMP	MGI:MGI:2429638	Mouse	PMID:11784869
Biological Process	GO:0035265	organ growth	Ly6e	IMP	MGI:MGI:2429638	Mouse	PMID:11784869
Biological Process	GO:0055010	ventricular cardiac muscle tissue morphogenesis	Ly6e	IMP	MGI:MGI:2429638	Mouse	PMID:11784869

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern