Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes LSM8
  • Mouse genes Lsm8
  • Rat genes Lsm8
  • Zfish genes lsm8
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Lsm8

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	LSM8	IPI	UniProtKB:Q9Y333	Human	PMID:14667819
Molecular Function	GO:0005515	protein binding	LSM8	IPI	UniProtKB:P62310	Human	PMID:15231747
Molecular Function	GO:0005515	protein binding	LSM8	IPI	UniProtKB:P62312	Human	PMID:15231747
Molecular Function	GO:0005515	protein binding	LSM8	IPI	UniProtKB:Q9Y333	Human	PMID:15231747
Molecular Function	GO:0005515	protein binding	LSM8	IPI	UniProtKB:Q9Y4Z0	Human	PMID:15231747
Molecular Function	GO:0005515	protein binding	LSM8	IPI	UniProtKB:Q9Y333	Human	PMID:19628699
Molecular Function	GO:0005515	protein binding	LSM8	IPI	UniProtKB:P62310	Human	PMID:21988832
Molecular Function	GO:0005515	protein binding	LSM8	IPI	UniProtKB:P62310	Human	PMID:22365833
Molecular Function	GO:0005515	protein binding	LSM8	IPI	UniProtKB:Q9Y333	Human	PMID:22365833
Molecular Function	GO:0005515	protein binding	LSM8	IPI	UniProtKB:P62312	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	LSM8	IPI	UniProtKB:D3DTS7	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	LSM8	IPI	UniProtKB:O60260-5	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	LSM8	IPI	UniProtKB:P00441	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	LSM8	IPI	UniProtKB:P09936	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	LSM8	IPI	UniProtKB:P37840	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	LSM8	IPI	UniProtKB:P42858	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	LSM8	IPI	UniProtKB:Q13148	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	LSM8	IPI	UniProtKB:Q14203-5	Human	PMID:32814053
Molecular Function	GO:0003723	RNA binding	LSM8	HDA		Human	PMID:22658674
Molecular Function	GO:0003723	RNA binding	LSM8	HDA		Human	PMID:22681889
Cellular Component	GO:0120115	Lsm2-8 complex	LSM8	IDA		Human	PMID:10523320
Cellular Component	GO:0005634	nucleus	LSM8	IDA		Human	PMID:26912367
Cellular Component	GO:0071005	U2-type precatalytic spliceosome	LSM8	IDA		Human	PMID:28781166
Cellular Component	GO:0046540	U4/U6 x U5 tri-snRNP complex	LSM8	IPI		Human	PMID:30975767
Cellular Component	GO:0046540	U4/U6 x U5 tri-snRNP complex	LSM8	IDA		Human	PMID:26912367
Biological Process	GO:0006397	mRNA processing	lsm8	IMP	ZFIN:ZDB-GENO-110111-3	Zfish	PMID:27880902
Biological Process	GO:0000398	mRNA splicing, via spliceosome	LSM8	IDA		Human	PMID:28781166
Biological Process	GO:0008380	RNA splicing	lsm8	IMP	ZFIN:ZDB-GENO-110111-3	Zfish	PMID:27880902
Biological Process	GO:0030217	T cell differentiation	lsm8	IMP	ZFIN:ZDB-GENO-110111-3	Zfish	PMID:27880902
Biological Process	GO:0030217	T cell differentiation	lsm8	IGI	ZFIN:ZDB-GENE-031112-9	Zfish	PMID:27880902

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern