Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes LRIG2
  • Mouse genes Lrig2
  • Rat genes Lrig2
  • Zfish genes lrig2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Lrig2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	LRIG2	IPI	UniProtKB:P00533	Human	PMID:25353163
Molecular Function	GO:0005515	protein binding	LRIG2	IPI	UniProtKB:P09619	Human	PMID:30015847
Molecular Function	GO:0005515	protein binding	Lrig2	IPI	PR:P13595	Mouse	PMID:26651291
Molecular Function	GO:0005515	protein binding	Lrig2	IPI	PR:O09126	Mouse	PMID:26651291
Molecular Function	GO:0005102	signaling receptor binding	Lrig2	IPI	PR:P97798	Mouse	PMID:26651291
Cellular Component	GO:0030426	growth cone	Lrig2	IDA		Mouse	PMID:26651291
Cellular Component	GO:0097708	intracellular vesicle	Lrig2	IDA		Mouse	PMID:26651291
Cellular Component	GO:0016020	membrane	Lrig2	IDA		Mouse	PMID:26651291
Biological Process	GO:0060384	innervation	Lrig2	IGI	MGI:MGI:107935	Mouse	PMID:24086156
Biological Process	GO:0006509	membrane protein ectodomain proteolysis	Lrig2	IMP		Mouse	PMID:26651291
Biological Process	GO:0048681	negative regulation of axon regeneration	Lrig2	IMP		Mouse	PMID:26651291
Biological Process	GO:0051045	negative regulation of membrane protein ectodomain proteolysis	Lrig2	IMP		Mouse	PMID:26651291
Biological Process	GO:0010977	negative regulation of neuron projection development	Lrig2	IGI	MGI:MGI:2679262	Mouse	PMID:26651291
Biological Process	GO:0010977	negative regulation of neuron projection development	Lrig2	IGI	MGI:MGI:1096335	Mouse	PMID:26651291
Biological Process	GO:2000010	positive regulation of protein localization to cell surface	Lrig2	IMP		Mouse	PMID:26651291
Biological Process	GO:0034394	protein localization to cell surface	Lrig2	IMP		Mouse	PMID:26651291
Biological Process	GO:0048679	regulation of axon regeneration	Lrig2	IGI	MGI:MGI:1096335	Mouse	PMID:26651291
Biological Process	GO:0048679	regulation of axon regeneration	Lrig2	IGI	MGI:MGI:1097159	Mouse	PMID:26651291
Biological Process	GO:2001222	regulation of neuron migration	Lrig2	IGI	MGI:MGI:1097159	Mouse	PMID:26651291
Biological Process	GO:2001222	regulation of neuron migration	Lrig2	IGI	MGI:MGI:1096335	Mouse	PMID:26651291
Biological Process	GO:0010640	regulation of platelet-derived growth factor receptor signaling pathway	Lrig2	IGI	MGI:MGI:97531	Mouse	PMID:24023893
Biological Process	GO:0007605	sensory perception of sound	Lrig2	IMP	MGI:MGI:4128231	Mouse	PMID:24086156

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern