Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes LRCH1
  • Mouse genes Lrch1
  • Rat genes Lrch1
  • Zfish genes lrch1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Lrch1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	LRCH1	IPI	UniProtKB:Q8NF50	Human	PMID:24255178
Molecular Function	GO:0005515	protein binding	LRCH1	IPI	UniProtKB:Q8NF50-2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	LRCH1	IPI	UniProtKB:Q8NF50	Human	PMID:28028151
Molecular Function	GO:0005515	protein binding	LRCH1	IPI	UniProtKB:Q8NF50	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	Lrch1	IPI	UniProtKB:Q8C147	Mouse	MGI:MGI:5824146|PMID:28028151
Cellular Component	GO:0005737	cytoplasm	LRCH1	IMP		Human	PMID:28028151
Biological Process	GO:1990869	cellular response to chemokine	LRCH1	IMP		Human	PMID:28028151
Biological Process	GO:1990869	cellular response to chemokine	Lrch1	IMP		Mouse	MGI:MGI:5824146|PMID:28028151
Biological Process	GO:0034260	negative regulation of GTPase activity	LRCH1	IDA		Human	PMID:28028151
Biological Process	GO:0034260	negative regulation of GTPase activity	Lrch1	IDA		Mouse	MGI:MGI:5824146|PMID:28028151
Biological Process	GO:2000405	negative regulation of T cell migration	LRCH1	IMP		Human	PMID:28028151
Biological Process	GO:2000405	negative regulation of T cell migration	Lrch1	IMP		Mouse	MGI:MGI:5824146|PMID:28028151

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern