Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes LPXN
  • Mouse genes Lpxn
  • Rat genes Lpxn
  • Zfish genes lpxn
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Lpxn

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	LPXN	IPI	UniProtKB:P07948	Human	PMID:17640867
Molecular Function	GO:0005515	protein binding	LPXN	IPI	UniProtKB:P10275	Human	PMID:18451096
Molecular Function	GO:0005515	protein binding	LPXN	IPI	UniProtKB:P11831	Human	PMID:18497331
Molecular Function	GO:0005515	protein binding	LPXN	IPI	UniProtKB:Q05397	Human	PMID:18497331
Molecular Function	GO:0005515	protein binding	LPXN	IPI	UniProtKB:P09022	Human	PMID:23088713
Molecular Function	GO:0005515	protein binding	LPXN	IPI	UniProtKB:P25800	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	LPXN	IPI	UniProtKB:P31274	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	LPXN	IPI	UniProtKB:Q06455-4	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	LPXN	IPI	UniProtKB:Q494U1	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	LPXN	IPI	UniProtKB:Q8IVE3	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	LPXN	IPI	UniProtKB:Q8N3L3	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	LPXN	IPI	UniProtKB:Q8IVE3	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	LPXN	IPI	UniProtKB:P31274	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	LPXN	IPI	UniProtKB:P01137	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LPXN	IPI	UniProtKB:P18206-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LPXN	IPI	UniProtKB:P21549	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LPXN	IPI	UniProtKB:P25800	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LPXN	IPI	UniProtKB:P29972	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LPXN	IPI	UniProtKB:P31274	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LPXN	IPI	UniProtKB:Q06455-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LPXN	IPI	UniProtKB:Q494U1-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LPXN	IPI	UniProtKB:Q63HR2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LPXN	IPI	UniProtKB:Q8TAP4-4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LPXN	IPI	UniProtKB:Q96HA1-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LPXN	IPI	UniProtKB:Q96CV9	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Lpxn	IPI	UniProtKB:P35831	Mouse	MGI:MGI:5306581|PMID:15786712
Molecular Function	GO:0005515	protein binding	Lpxn	IPI	UniProtKB:P29352|UniProtKB:P34152|UniProtKB:P35831	Mouse	MGI:MGI:5306321|PMID:12674328
Molecular Function	GO:0005515	protein binding	Lpxn	IPI	UniProtKB:Q9QVP9	Mouse	MGI:MGI:5306581|PMID:15786712
Molecular Function	GO:0005515	protein binding	Lpxn	IPI	UniProtKB:P25911	Mouse	MGI:MGI:3722965|PMID:17640867
Molecular Function	GO:0005515	protein binding	Lpxn	IPI	UniProtKB:Q05397	Mouse	MGI:MGI:5306566|PMID:19917054
Molecular Function	GO:0003712	transcription coregulator activity	LPXN	IDA		Human	PMID:18451096
Molecular Function	GO:0003712	transcription coregulator activity	LPXN	IDA		Human	PMID:18497331
Molecular Function	GO:0003712	transcription coregulator activity	Lpxn	IDA		Mouse	MGI:MGI:5315692|PMID:18497331
Cellular Component	GO:0005737	cytoplasm	LPXN	IDA		Human	PMID:17640867
Cellular Component	GO:0005737	cytoplasm	LPXN	IDA		Human	PMID:18451096
Cellular Component	GO:0005737	cytoplasm	LPXN	IDA		Human	PMID:18497331
Cellular Component	GO:0005829	cytosol	LPXN	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005925	focal adhesion	LPXN	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005925	focal adhesion	LPXN	IDA		Human	PMID:18451096
Cellular Component	GO:0005925	focal adhesion	LPXN	IDA		Human	PMID:18497331
Cellular Component	GO:0005925	focal adhesion	LPXN	IDA		Human	PMID:20543562
Cellular Component	GO:0005925	focal adhesion	Lpxn	IDA		Mouse	MGI:MGI:5306566|PMID:19917054
Cellular Component	GO:0016020	membrane	LPXN	HDA		Human	PMID:19946888
Cellular Component	GO:0016607	nuclear speck	LPXN	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	LPXN	IDA		Human	PMID:18451096
Cellular Component	GO:0005634	nucleus	LPXN	IDA		Human	PMID:18497331
Cellular Component	GO:0005634	nucleus	Lpxn	IDA		Mouse	MGI:MGI:5315692|PMID:18497331
Cellular Component	GO:0005886	plasma membrane	LPXN	IDA		Human	PMID:17640867
Cellular Component	GO:0002102	podosome	LPXN	IDA		Human	PMID:12674328
Cellular Component	GO:0002102	podosome	Lpxn	IDA		Mouse	MGI:MGI:5306321|PMID:12674328
Biological Process	GO:0050859	negative regulation of B cell receptor signaling pathway	LPXN	IDA		Human	PMID:17640867
Biological Process	GO:0050859	negative regulation of B cell receptor signaling pathway	Lpxn	IDA		Mouse	MGI:MGI:3722965|PMID:17640867
Biological Process	GO:0007162	negative regulation of cell adhesion	LPXN	IDA		Human	PMID:20543562
Biological Process	GO:0033628	regulation of cell adhesion mediated by integrin	Lpxn	IMP		Mouse	MGI:MGI:5306566|PMID:19917054

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern