Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes LMOD2
  • Mouse genes Lmod2
  • Rat genes Lmod2
  • Zfish genes lmod2a,lmod2b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Lmod2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003779	actin binding	LMOD2	IDA		Human	PMID:18403713
Molecular Function	GO:0003779	actin binding	LMOD2	IDA		Human	PMID:20685966
Molecular Function	GO:0003779	actin binding	LMOD2	IDA		Human	PMID:26370058
Molecular Function	GO:0003785	actin monomer binding	LMOD2	IMP		Human	PMID:25250574
Molecular Function	GO:0005523	tropomyosin binding	LMOD2	IMP		Human	PMID:25250574
Cellular Component	GO:0005884	actin filament	LMOD2	IDA		Human	PMID:26370058
Cellular Component	GO:0097512	cardiac myofibril	Lmod2	IDA		Rat	PMID:20685966|RGD:11344944
Cellular Component	GO:0031430	M band	LMOD2	IDA		Human	PMID:18403713
Cellular Component	GO:0031430	M band	LMOD2	IDA		Human	PMID:20685966
Cellular Component	GO:0031430	M band	Lmod2	IDA		Rat	PMID:18403713|RGD:11344939
Cellular Component	GO:0030016	myofibril	LMOD2	IDA		Human	PMID:20685966
Cellular Component	GO:0030017	sarcomere	LMOD2	IDA		Human	PMID:18403713
Cellular Component	GO:0030017	sarcomere	LMOD2	IDA		Human	PMID:20685966
Cellular Component	GO:0030017	sarcomere	LMOD2	IDA		Human	PMID:26370058
Cellular Component	GO:0030017	sarcomere	Lmod2	IDA		Rat	PMID:18403713|RGD:11344939
Biological Process	GO:0030041	actin filament polymerization	Lmod2	IMP		Mouse	MGI:MGI:5700101|PMID:26487682
Biological Process	GO:0045010	actin nucleation	LMOD2	IDA		Human	PMID:20685966
Biological Process	GO:0045010	actin nucleation	LMOD2	IMP		Human	PMID:25250574
Biological Process	GO:0045010	actin nucleation	LMOD2	IDA		Human	PMID:26370058
Biological Process	GO:0030838	positive regulation of actin filament polymerization	LMOD2	IDA		Human	PMID:26370058
Biological Process	GO:0045214	sarcomere organization	LMOD2	IMP		Human	PMID:18403713
Biological Process	GO:0045214	sarcomere organization	Lmod2	IMP		Mouse	MGI:MGI:5787841|PMID:27274810
Biological Process	GO:0045214	sarcomere organization	Lmod2	IMP		Rat	PMID:18403713|RGD:11344939

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern