Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes LHFPL4
  • Mouse genes Lhfpl4
  • Rat genes Lhfpl4
  • Zfish genes lhfpl4a,lhfpl4b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Lhfpl4

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0050811	GABA receptor binding	Lhfpl4	IDA		Mouse	MGI:MGI:6104059|PMID:28978485
Molecular Function	GO:0050811	GABA receptor binding	Lhfpl4	IDA		Mouse	MGI:MGI:6201911|PMID:29742426
Molecular Function	GO:0050811	GABA receptor binding	Lhfpl4	IDA		Rat	PMID:28279354|RGD:13800541
Molecular Function	GO:0005515	protein binding	LHFPL4	IPI	UniProtKB:P62812	Human	PMID:28978485
Molecular Function	GO:0005515	protein binding	LHFPL4	IPI	UniProtKB:Q9Y6I9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Lhfpl4	IPI	UniProtKB:P18507|UniProtKB:P26048|UniProtKB:P63080	Mouse	MGI:MGI:6104059|PMID:28978485
Molecular Function	GO:0005515	protein binding	Lhfpl4	IPI	UniProtKB:P22723|UniProtKB:P62812	Mouse	MGI:MGI:6201911|PMID:29742426
Molecular Function	GO:0005515	protein binding	Lhfpl4	IPI	UniProtKB:Q69ZK9	Mouse	MGI:MGI:6201911|PMID:29742426
Molecular Function	GO:0005515	protein binding	Lhfpl4	IPI	UniProtKB:P18508,UniProtKB:P62813,UniProtKB:P63079,UniProtKB:P63138,UniProtKB:Q62888	Rat	PMID:28279354|RGD:13800541
Molecular Function	GO:0005515	protein binding	Lhfpl4	IPI	UniProtKB:P62813	Rat	PMID:28279354|RGD:13800541
Molecular Function	GO:0005515	protein binding	Lhfpl4	IPI	UniProtKB:Q7TSY2	Rat	PMID:28279354|RGD:13800541
Cellular Component	GO:0098982	GABA-ergic synapse	Lhfpl4	IDA		Mouse	PMID:28279354
Cellular Component	GO:0098982	GABA-ergic synapse	Lhfpl4	IMP		Mouse	PMID:28279354
Cellular Component	GO:0098982	GABA-ergic synapse	Lhfpl4	IPI		Mouse	PMID:28279354
Cellular Component	GO:0098982	GABA-ergic synapse	Lhfpl4	IEP		Mouse	PMID:28279354
Cellular Component	GO:0060077	inhibitory synapse	Lhfpl4	IDA		Mouse	MGI:MGI:6201911|PMID:29742426
Cellular Component	GO:0060077	inhibitory synapse	Lhfpl4	IDA		Rat	PMID:28978485|RGD:13792522
Cellular Component	GO:0045211	postsynaptic membrane	Lhfpl4	IDA		Mouse	MGI:MGI:6104059|PMID:28978485
Cellular Component	GO:0045211	postsynaptic membrane	Lhfpl4	IMP		Mouse	MGI:MGI:6201911|PMID:29742426
Cellular Component	GO:0099572	postsynaptic specialization	Lhfpl4	IPI		Mouse	PMID:28279354
Cellular Component	GO:0099572	postsynaptic specialization	Lhfpl4	IDA		Mouse	PMID:28279354
Cellular Component	GO:0099572	postsynaptic specialization	Lhfpl4	IEP		Mouse	PMID:28279354
Biological Process	GO:0097112	gamma-aminobutyric acid receptor clustering	Lhfpl4	IMP		Mouse	MGI:MGI:6114387|PMID:28279354
Biological Process	GO:0097112	gamma-aminobutyric acid receptor clustering	Lhfpl4	IMP		Mouse	MGI:MGI:6104059|PMID:28978485
Biological Process	GO:0099645	neurotransmitter receptor localization to postsynaptic specialization membrane	Lhfpl4	IMP		Mouse	PMID:28279354
Biological Process	GO:0099645	neurotransmitter receptor localization to postsynaptic specialization membrane	Lhfpl4	IDA		Mouse	PMID:28279354
Biological Process	GO:1905702	regulation of inhibitory synapse assembly	Lhfpl4	IMP		Mouse	MGI:MGI:6201911|PMID:29742426

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern