Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes LETMD1
  • Mouse genes Letmd1
  • Rat genes Letmd1
  • Zfish genes letmd1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Letmd1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0001671	ATPase activator activity	Letmd1	IDA		Mouse	PMID:34910916
Molecular Function	GO:0008047	enzyme activator activity	Letmd1	IDA		Mouse	PMID:34910916
Molecular Function	GO:0060090	molecular adaptor activity	Letmd1	IDA		Mouse	PMID:34910916
Molecular Function	GO:0005515	protein binding	LETMD1	IPI	UniProtKB:Q00765	Human	PMID:16762630
Molecular Function	GO:0005515	protein binding	LETMD1	IPI	UniProtKB:Q8WY22	Human	PMID:17943721
Molecular Function	GO:0005515	protein binding	LETMD1	IPI	UniProtKB:P02654	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LETMD1	IPI	UniProtKB:P55056	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LETMD1	IPI	UniProtKB:Q6NTF9-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LETMD1	IPI	UniProtKB:Q9NRX6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Letmd1	IPI	UniProtKB:Q3TKT4	Mouse	MGI:MGI:6881858|PMID:34910916
Cellular Component	GO:0005743	mitochondrial inner membrane	Letmd1	IDA		Mouse	MGI:MGI:7388014|PMID:36334589
Cellular Component	GO:0005739	mitochondrion	LETMD1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005739	mitochondrion	Letmd1	HDA		Mouse	PMID:18614015
Cellular Component	GO:0005730	nucleolus	LETMD1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	LETMD1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	Letmd1	IDA		Mouse	PMID:34910916
Biological Process	GO:0007005	mitochondrion organization	Letmd1	IMP		Mouse	MGI:MGI:6844901|PMID:34669999
Biological Process	GO:0120162	positive regulation of cold-induced thermogenesis	Letmd1	IDA		Mouse	MGI:MGI:7388014|PMID:36334589
Biological Process	GO:0120162	positive regulation of cold-induced thermogenesis	Letmd1	IDA		Mouse	PMID:34910916
Biological Process	GO:0050727	regulation of inflammatory response	LETMD1	IMP		Human	PMID:31980577
Biological Process	GO:0050764	regulation of phagocytosis	LETMD1	IMP		Human	PMID:31980577

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern