Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes LEO1
  • Mouse genes Leo1
  • Rat genes Leo1
  • Zfish genes leo1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Leo1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	LEO1	IPI	UniProtKB:Q6P1J9	Human	PMID:15923622
Molecular Function	GO:0005515	protein binding	LEO1	IPI	UniProtKB:Q6P1J9	Human	PMID:16024656
Molecular Function	GO:0005515	protein binding	LEO1	IPI	UniProtKB:Q8N7H5	Human	PMID:16024656
Molecular Function	GO:0005515	protein binding	LEO1	IPI	UniProtKB:P35222	Human	PMID:16630820
Molecular Function	GO:0005515	protein binding	LEO1	IPI	UniProtKB:Q6P1J9	Human	PMID:19136632
Molecular Function	GO:0005515	protein binding	LEO1	IPI	UniProtKB:Q8N7H5	Human	PMID:19410543
Molecular Function	GO:0005515	protein binding	LEO1	IPI	UniProtKB:P23193	Human	PMID:20178742
Molecular Function	GO:0005515	protein binding	LEO1	IPI	UniProtKB:Q6P1J9	Human	PMID:20178742
Molecular Function	GO:0005515	protein binding	LEO1	IPI	UniProtKB:Q8N7H5	Human	PMID:20178742
Molecular Function	GO:0005515	protein binding	LEO1	IPI	UniProtKB:Q6P1J9	Human	PMID:24981860
Molecular Function	GO:0005515	protein binding	LEO1	IPI	UniProtKB:Q8N7H5	Human	PMID:24981860
Molecular Function	GO:0005515	protein binding	LEO1	IPI	UniProtKB:Q8N7H5	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	LEO1	IPI	UniProtKB:Q6P1J9	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	LEO1	IPI	UniProtKB:Q8N7H5	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	LEO1	IPI	UniProtKB:Q6P1J9	Human	PMID:29774127
Molecular Function	GO:0005515	protein binding	LEO1	IPI	UniProtKB:O75764	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LEO1	IPI	UniProtKB:Q6PI77	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LEO1	IPI	UniProtKB:Q8N7H5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Leo1	IPI	UniProtKB:P83870	Mouse	MGI:MGI:6203683|PMID:27749823
Molecular Function	GO:0005515	protein binding	Leo1	IPI	UniProtKB:Q5XJV7	Mouse	MGI:MGI:5812827|PMID:27864380
Molecular Function	GO:0005515	protein binding	Leo1	IPI	PR:Q8JZM7	Mouse	PMID:22252316
Molecular Function	GO:0005515	protein binding	Leo1	IPI	PR:Q8K2T8	Mouse	PMID:22252316
Cellular Component	GO:0016593	Cdc73/Paf1 complex	LEO1	IDA		Human	PMID:16307923
Cellular Component	GO:0016593	Cdc73/Paf1 complex	LEO1	IDA		Human	PMID:18987311
Cellular Component	GO:0016593	Cdc73/Paf1 complex	LEO1	IDA		Human	PMID:20178742
Cellular Component	GO:0016593	Cdc73/Paf1 complex	leo1	IDA		Zfish	PMID:21338598
Cellular Component	GO:0005813	centrosome	LEO1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0001650	fibrillar center	LEO1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	LEO1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	leo1	IDA		Zfish	PMID:20178782
Biological Process	GO:0048701	embryonic cranial skeleton morphogenesis	leo1	IMP	ZFIN:ZDB-GENO-100628-6	Zfish	PMID:20178782
Biological Process	GO:0001711	endodermal cell fate commitment	Leo1	IMP		Mouse	MGI:MGI:3849235|PMID:19345177
Biological Process	GO:0021782	glial cell development	leo1	IMP	ZFIN:ZDB-GENO-100628-6	Zfish	PMID:20178782
Biological Process	GO:0007507	heart development	leo1	IMP	ZFIN:ZDB-GENO-100628-6	Zfish	PMID:20178782
Biological Process	GO:0030318	melanocyte differentiation	leo1	IMP	ZFIN:ZDB-GENO-100628-6	Zfish	PMID:20178782
Biological Process	GO:0006378	mRNA polyadenylation	LEO1	IMP		Human	PMID:21329879
Biological Process	GO:0045638	negative regulation of myeloid cell differentiation	LEO1	IDA		Human	PMID:20541477
Biological Process	GO:0014032	neural crest cell development	leo1	IMP	ZFIN:ZDB-GENO-100628-6	Zfish	PMID:20178782
Biological Process	GO:0031442	positive regulation of mRNA 3'-end processing	LEO1	IMP		Human	PMID:21329879
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	LEO1	IDA		Human	PMID:16307923
Biological Process	GO:0021529	spinal cord oligodendrocyte cell differentiation	leo1	IMP	ZFIN:ZDB-GENO-120718-5	Zfish	PMID:22699901
Biological Process	GO:0019827	stem cell population maintenance	LEO1	IDA		Human	PMID:19345177
Biological Process	GO:0019827	stem cell population maintenance	Leo1	IMP		Mouse	MGI:MGI:3849235|PMID:19345177
Biological Process	GO:0006368	transcription elongation by RNA polymerase II	LEO1	IDA		Human	PMID:20178742
Biological Process	GO:0050936	xanthophore differentiation	leo1	IMP	ZFIN:ZDB-GENO-100628-6	Zfish	PMID:20178782

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern