Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes LEMD3
  • Mouse genes Lemd3
  • Rat genes Lemd3
  • Zfish genes lemd3
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Lemd3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	LEMD3	IPI	UniProtKB:Q15797	Human	PMID:15231748
Molecular Function	GO:0005515	protein binding	LEMD3	IPI	UniProtKB:P84022	Human	PMID:15647271
Molecular Function	GO:0005515	protein binding	LEMD3	IPI	UniProtKB:Q15796	Human	PMID:15647271
Molecular Function	GO:0005515	protein binding	LEMD3	IPI	UniProtKB:Q15797	Human	PMID:15647271
Molecular Function	GO:0005515	protein binding	LEMD3	IPI	UniProtKB:Q99717	Human	PMID:15647271
Molecular Function	GO:0005515	protein binding	LEMD3	IPI	UniProtKB:Q9ULZ3	Human	PMID:24407287
Molecular Function	GO:0005515	protein binding	LEMD3	IPI	UniProtKB:O15198-2	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	LEMD3	IPI	UniProtKB:O15198-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LEMD3	IPI	UniProtKB:Q15797	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LEMD3	IPI	UniProtKB:Q9H6H4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LEMD3	IPI	UniProtKB:Q9UI14	Human	PMID:32296183
Cellular Component	GO:0016020	membrane	LEMD3	IDA		Human	PMID:10671519
Cellular Component	GO:0005635	nuclear envelope	Lemd3	IDA		Mouse	PMID:10671519
Cellular Component	GO:0005637	nuclear inner membrane	LEMD3	IDA		Human	PMID:15647271
Cellular Component	GO:0031965	nuclear membrane	LEMD3	IDA		Human	GO_REF:0000052
Biological Process	GO:0001525	angiogenesis	Lemd3	IMP	MGI:MGI:3703328	Mouse	PMID:16943282
Biological Process	GO:0002044	blood vessel endothelial cell migration involved in intussusceptive angiogenesis	Lemd3	IMP	MGI:MGI:3703328	Mouse	PMID:16943282
Biological Process	GO:0061300	cerebellum vasculature development	lemd3	IMP	ZFIN:ZDB-MRPHLNO-181218-2	Zfish	PMID:30120215
Biological Process	GO:0061300	cerebellum vasculature development	lemd3	IMP	ZFIN:ZDB-MRPHLNO-181218-3	Zfish	PMID:30120215
Biological Process	GO:0032926	negative regulation of activin receptor signaling pathway	LEMD3	IDA		Human	PMID:15647271
Biological Process	GO:0030514	negative regulation of BMP signaling pathway	LEMD3	IDA		Human	PMID:15647271
Biological Process	GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway	LEMD3	IDA		Human	PMID:15647271
Biological Process	GO:0006997	nucleus organization	Lemd3	IMP	MGI:MGI:3703328	Mouse	PMID:16943282
Biological Process	GO:0051726	regulation of cell cycle	Lemd3	IMP		Mouse	PMID:19720741
Biological Process	GO:1903053	regulation of extracellular matrix organization	Lemd3	IMP	MGI:MGI:3703328	Mouse	PMID:16943282
Biological Process	GO:0035914	skeletal muscle cell differentiation	Lemd3	IMP		Mouse	PMID:19720741

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern