Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes LDB2
  • Mouse genes Ldb2
  • Rat genes Ldb2
  • Zfish genes ldb2a,ldb2b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ldb2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003682	chromatin binding	ldb2a	IDA		Zfish	PMID:25665164
Molecular Function	GO:0019899	enzyme binding	Ldb2	IPI	UniProtKB:Q9WTV7	Mouse	MGI:MGI:4456957|PMID:11882901
Molecular Function	GO:0005515	protein binding	LDB2	IPI	UniProtKB:P61968	Human	PMID:15231748
Molecular Function	GO:0005515	protein binding	LDB2	IPI	UniProtKB:P61968	Human	PMID:18330356
Molecular Function	GO:0005515	protein binding	LDB2	IPI	UniProtKB:Q99598	Human	PMID:18330356
Molecular Function	GO:0005515	protein binding	LDB2	IPI	UniProtKB:Q9BWW4	Human	PMID:18330356
Molecular Function	GO:0005515	protein binding	LDB2	IPI	UniProtKB:P61968	Human	PMID:20211142
Molecular Function	GO:0005515	protein binding	LDB2	IPI	UniProtKB:Q9BWW4	Human	PMID:20211142
Molecular Function	GO:0005515	protein binding	LDB2	IPI	UniProtKB:O00560	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LDB2	IPI	UniProtKB:O15182	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LDB2	IPI	UniProtKB:P20618	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LDB2	IPI	UniProtKB:P25791-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LDB2	IPI	UniProtKB:P25800	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LDB2	IPI	UniProtKB:P61968	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LDB2	IPI	UniProtKB:Q68G74	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LDB2	IPI	UniProtKB:Q6DKK2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LDB2	IPI	UniProtKB:Q7L775	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LDB2	IPI	UniProtKB:Q86VI1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LDB2	IPI	UniProtKB:Q8TAP4-4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LDB2	IPI	UniProtKB:Q8TBB1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LDB2	IPI	UniProtKB:Q8WUI4-6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LDB2	IPI	UniProtKB:Q969H8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LDB2	IPI	UniProtKB:Q96GM5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LDB2	IPI	UniProtKB:Q96HA8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LDB2	IPI	UniProtKB:Q99598	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LDB2	IPI	UniProtKB:Q9BVM4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LDB2	IPI	UniProtKB:Q9BY27	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LDB2	IPI	UniProtKB:Q9H6Z9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LDB2	IPI	UniProtKB:Q9NWQ9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Ldb2	IPI	UniProtKB:Q9WTV7	Mouse	MGI:MGI:6092914|PMID:17848518
Molecular Function	GO:0005515	protein binding	Ldb2	IPI	UniProtKB:O54988	Mouse	MGI:MGI:5751678|PMID:19675209
Molecular Function	GO:0005515	protein binding	Ldb2	IPI	PR:P61969	Mouse	PMID:9860983
Molecular Function	GO:0005515	protein binding	Ldb2	IPI	PR:Q9WTV7	Mouse	PMID:10431247
Cellular Component	GO:0031252	cell leading edge	Ldb2	IDA		Mouse	MGI:MGI:5751678|PMID:19675209
Cellular Component	GO:0005730	nucleolus	LDB2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	LDB2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	LDB2	IDA		Human	PMID:9853615
Cellular Component	GO:0005886	plasma membrane	LDB2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005667	transcription regulator complex	Ldb2	IDA		Mouse	PMID:9192866
Biological Process	GO:0044085	cellular component biogenesis	Ldb2	IGI	MGI:MGI:894762	Mouse	PMID:17991461
Biological Process	GO:0010669	epithelial structure maintenance	Ldb2	IGI	MGI:MGI:894762	Mouse	PMID:17991461
Biological Process	GO:0001942	hair follicle development	Ldb2	IGI	MGI:MGI:894762	Mouse	PMID:17991461
Biological Process	GO:0030514	negative regulation of BMP signaling pathway	ldb2a	IMP	ZFIN:ZDB-MRPHLNO-150506-3	Zfish	PMID:25665164
Biological Process	GO:1900108	negative regulation of nodal signaling pathway	ldb2a	IMP	ZFIN:ZDB-MRPHLNO-150506-3	Zfish	PMID:25665164
Biological Process	GO:0044089	positive regulation of cellular component biogenesis	Ldb2	IGI	MGI:MGI:894762	Mouse	PMID:17991461
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Ldb2	IGI	MGI:MGI:102673	Mouse	PMID:9192866
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Ldb2	IGI	MGI:MGI:102673	Mouse	PMID:10431247
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Ldb2	IGI	MGI:MGI:107374	Mouse	PMID:10431247
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Ldb2	IGI	MGI:MGI:1342291	Mouse	PMID:10431247
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Ldb2	IGI	MGI:MGI:107374	Mouse	PMID:9192866
Biological Process	GO:0030334	regulation of cell migration	Ldb2	IMP	UniProtKB:O54988	Mouse	MGI:MGI:5751678|PMID:19675209
Biological Process	GO:0043549	regulation of kinase activity	Ldb2	IDA		Mouse	MGI:MGI:5751678|PMID:19675209
Biological Process	GO:0035019	somatic stem cell population maintenance	Ldb2	IGI	MGI:MGI:894762	Mouse	PMID:17991461
Biological Process	GO:0002040	sprouting angiogenesis	ldb2a	IMP	ZFIN:ZDB-MRPHLNO-180301-1,ZFIN:ZDB-MRPHLNO-180302-1	Zfish	PMID:28946938

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern