Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes LAPTM4B
  • Mouse genes Laptm4b
  • Rat genes Laptm4b
  • Zfish genes laptm4b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Laptm4b

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0097001	ceramide binding	LAPTM4B	IDA		Human	PMID:26280656
Molecular Function	GO:0019900	kinase binding	LAPTM4B	IPI	UniProtKB:O60331	Human	PMID:25588945
Molecular Function	GO:1902936	phosphatidylinositol bisphosphate binding	LAPTM4B	IDA		Human	PMID:25588945
Molecular Function	GO:0005515	protein binding	LAPTM4B	IPI	UniProtKB:P08183	Human	PMID:20711237
Molecular Function	GO:0005515	protein binding	LAPTM4B	IPI	UniProtKB:Q9GZU1	Human	PMID:21224396
Molecular Function	GO:0005515	protein binding	LAPTM4B	IPI	UniProtKB:P46934	Human	PMID:22096579
Molecular Function	GO:0005515	protein binding	LAPTM4B	IPI	UniProtKB:Q58DX5	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	LAPTM4B	IPI	UniProtKB:O14964	Human	PMID:25588945
Molecular Function	GO:0005515	protein binding	LAPTM4B	IPI	UniProtKB:Q9Y5X3	Human	PMID:25588945
Molecular Function	GO:0005515	protein binding	LAPTM4B	IPI	UniProtKB:P00533	Human	PMID:25594178
Molecular Function	GO:0005515	protein binding	LAPTM4B	IPI	UniProtKB:Q96A65	Human	PMID:25594178
Molecular Function	GO:0005515	protein binding	LAPTM4B	IPI	UniProtKB:P08195|UniProtKB:Q01650	Human	PMID:25998567
Molecular Function	GO:0005515	protein binding	LAPTM4B	IPI	UniProtKB:Q14392	Human	PMID:26126825
Molecular Function	GO:0005515	protein binding	LAPTM4B	IPI	UniProtKB:P00533	Human	PMID:28479384
Molecular Function	GO:0005515	protein binding	LAPTM4B	IPI	UniProtKB:Q14457	Human	PMID:28479384
Molecular Function	GO:0005515	protein binding	LAPTM4B	IPI	UniProtKB:A5PKU2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LAPTM4B	IPI	UniProtKB:P17181	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LAPTM4B	IPI	UniProtKB:P24593	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LAPTM4B	IPI	UniProtKB:P48165	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LAPTM4B	IPI	UniProtKB:P54849	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LAPTM4B	IPI	UniProtKB:Q02297-10	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LAPTM4B	IPI	UniProtKB:Q14108	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LAPTM4B	IPI	UniProtKB:Q2M2E3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LAPTM4B	IPI	UniProtKB:Q4LDR2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LAPTM4B	IPI	UniProtKB:Q6UXK2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LAPTM4B	IPI	UniProtKB:Q8N661	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LAPTM4B	IPI	UniProtKB:Q8NBI2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LAPTM4B	IPI	UniProtKB:Q8TED1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LAPTM4B	IPI	UniProtKB:Q96FB2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LAPTM4B	IPI	UniProtKB:Q99675	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LAPTM4B	IPI	UniProtKB:Q9H2K0	Human	PMID:32296183
Molecular Function	GO:0031625	ubiquitin protein ligase binding	LAPTM4B	IPI	UniProtKB:P46934	Human	PMID:25588945
Cellular Component	GO:0042995	cell projection	LAPTM4B	IDA		Human	PMID:22096579
Cellular Component	GO:0005769	early endosome	LAPTM4B	IDA		Human	PMID:25588945
Cellular Component	GO:0005768	endosome	LAPTM4B	IDA		Human	PMID:25588945
Cellular Component	GO:0031902	late endosome membrane	LAPTM4B	IDA		Human	PMID:21224396
Cellular Component	GO:0031902	late endosome membrane	LAPTM4B	IDA		Human	PMID:22096579
Cellular Component	GO:0031902	late endosome membrane	LAPTM4B	IDA		Human	PMID:25588945
Cellular Component	GO:0005765	lysosomal membrane	LAPTM4B	IDA		Human	PMID:21224396
Cellular Component	GO:0005765	lysosomal membrane	LAPTM4B	IDA		Human	PMID:22096579
Cellular Component	GO:0005764	lysosome	LAPTM4B	IDA		Human	PMID:25588945
Cellular Component	GO:0032585	multivesicular body membrane	LAPTM4B	IDA		Human	PMID:25588945
Cellular Component	GO:0032585	multivesicular body membrane	LAPTM4B	IDA		Human	PMID:26280656
Cellular Component	GO:0097487	multivesicular body, internal vesicle	LAPTM4B	IDA		Human	PMID:26280656
Cellular Component	GO:0005886	plasma membrane	LAPTM4B	IDA		Human	PMID:22096579
Biological Process	GO:0007032	endosome organization	LAPTM4B	IMP		Human	PMID:21224396
Biological Process	GO:0032509	endosome transport via multivesicular body sorting pathway	LAPTM4B	IDA		Human	PMID:25588945
Biological Process	GO:1905166	negative regulation of lysosomal protein catabolic process	LAPTM4B	IMP		Human	PMID:25588945
Biological Process	GO:0032911	negative regulation of transforming growth factor beta1 production	LAPTM4B	IDA		Human	PMID:26126825
Biological Process	GO:0097213	regulation of lysosomal membrane permeability	LAPTM4B	IMP		Human	PMID:26280656
Biological Process	GO:1905671	regulation of lysosome organization	LAPTM4B	IMP		Human	PMID:26280656

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern