Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes KYNU
  • Mouse genes Kynu
  • Rat genes Kynu
  • Zfish genes kynu
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Kynu

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0061981	3-hydroxykynureninase activity	KYNU	IDA		Human	PMID:28792876
Molecular Function	GO:0030429	kynureninase activity	KYNU	IDA		Human	PMID:11985583
Molecular Function	GO:0030429	kynureninase activity	KYNU	IMP		Human	PMID:17334708
Molecular Function	GO:0030429	kynureninase activity	KYNU	IDA		Human	PMID:9180257
Molecular Function	GO:0030429	kynureninase activity	Kynu	IDA		Rat	PMID:3400092|RGD:2290313
Molecular Function	GO:0030429	kynureninase activity	Kynu	IDA		Rat	PMID:7236232|RGD:2303721
Molecular Function	GO:0030429	kynureninase activity	Kynu	IDA		Rat	PMID:7451426|RGD:2290547
Molecular Function	GO:0042803	protein homodimerization activity	KYNU	IDA		Human	PMID:11985583
Molecular Function	GO:0030170	pyridoxal phosphate binding	Kynu	IDA		Rat	PMID:7451426|RGD:2290547
Cellular Component	GO:0005829	cytosol	KYNU	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005829	cytosol	KYNU	IDA		Human	PMID:6468727
Cellular Component	GO:0005829	cytosol	Kynu	IDA		Rat	PMID:7451426|RGD:2290547
Cellular Component	GO:0005739	mitochondrion	KYNU	IDA		Human	PMID:6468727
Cellular Component	GO:0005739	mitochondrion	Kynu	HDA		Mouse	PMID:18614015
Cellular Component	GO:0005654	nucleoplasm	KYNU	IDA		Human	GO_REF:0000052
Biological Process	GO:0007568	aging	Kynu	IEP		Rat	PMID:15970278|RGD:13703059
Biological Process	GO:0043420	anthranilate metabolic process	KYNU	IDA		Human	PMID:11985583
Biological Process	GO:0009435	NAD biosynthetic process	KYNU	IMP		Human	PMID:28792876
Biological Process	GO:0019805	quinolinate biosynthetic process	KYNU	IDA		Human	PMID:9291104
Biological Process	GO:0034341	response to type II interferon	KYNU	IDA		Human	PMID:9291104
Biological Process	GO:0034516	response to vitamin B6	KYNU	IMP		Human	PMID:1939450
Biological Process	GO:0006569	tryptophan catabolic process	KYNU	IMP		Human	PMID:17334708
Biological Process	GO:0019442	tryptophan catabolic process to acetyl-CoA	Kynu	IDA		Rat	PMID:7236232|RGD:2303721

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern