Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes KRT5
  • Mouse genes Krt5
  • Rat genes Krt5
  • Zfish genes krt5
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Krt5

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	KRT5	IPI	UniProtKB:P18054	Human	PMID:10727209
Molecular Function	GO:0005515	protein binding	KRT5	IPI	UniProtKB:P02533	Human	PMID:10852826
Molecular Function	GO:0005515	protein binding	KRT5	IPI	UniProtKB:Q13835-2	Human	PMID:10852826
Molecular Function	GO:0005515	protein binding	KRT5	IPI	UniProtKB:P02533,UniProtKB:P58107	Human	PMID:15671067
Molecular Function	GO:0005515	protein binding	KRT5	IPI	UniProtKB:Q9BT92	Human	PMID:15731013
Molecular Function	GO:0005515	protein binding	KRT5	IPI	UniProtKB:P02533	Human	PMID:22705788
Molecular Function	GO:0005515	protein binding	KRT5	IPI	UniProtKB:P02533	Human	PMID:24940650
Molecular Function	GO:0005515	protein binding	KRT5	IPI	UniProtKB:Q15149	Human	PMID:24940650
Molecular Function	GO:0005515	protein binding	KRT5	IPI	UniProtKB:O76015	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	KRT5	IPI	UniProtKB:P19012	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	KRT5	IPI	UniProtKB:Q15323	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	KRT5	IPI	UniProtKB:Q6A162	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	KRT5	IPI	UniProtKB:Q9BVG8	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	KRT5	IPI	UniProtKB:P02533	Human	PMID:31995743
Molecular Function	GO:0005515	protein binding	KRT5	IPI	UniProtKB:O76015	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT5	IPI	UniProtKB:P08727	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT5	IPI	UniProtKB:P08779	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT5	IPI	UniProtKB:P19012	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT5	IPI	UniProtKB:Q0VD86	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT5	IPI	UniProtKB:Q15323	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT5	IPI	UniProtKB:Q2M2I5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT5	IPI	UniProtKB:Q6A162	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT5	IPI	UniProtKB:Q7Z3Y7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT5	IPI	UniProtKB:Q7Z3Y8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT5	IPI	UniProtKB:Q7Z3Z0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT5	IPI	UniProtKB:Q92764	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT5	IPI	UniProtKB:Q9BVG8-5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Krt5	IPI	UniProtKB:P63277	Mouse	MGI:MGI:2662799|PMID:12657653
Molecular Function	GO:0005515	protein binding	Krt5	IPI	UniProtKB:Q61781|UniProtKB:Q9QXS1	Mouse	MGI:MGI:7260090|PMID:24940650
Molecular Function	GO:0005515	protein binding	Krt5	IPI	UniProtKB:Q8R0W0	Mouse	MGI:MGI:3805230|PMID:18285451
Molecular Function	GO:0005515	protein binding	Krt5	IPI	UniProtKB:P27628	Mouse	PMID:11063033
Molecular Function	GO:0097110	scaffold protein binding	KRT5	IPI	UniProtKB:Q13835	Human	PMID:10852826
Molecular Function	GO:0097110	scaffold protein binding	KRT5	IPI	UniProtKB:Q99959	Human	PMID:10852826
Cellular Component	GO:0001533	cornified envelope	Krt5	IDA		Mouse	PMID:26644517
Cellular Component	GO:0005737	cytoplasm	KRT5	IDA		Human	PMID:20128788
Cellular Component	GO:0005737	cytoplasm	KRT5	IDA		Human	PMID:22170488
Cellular Component	GO:0005737	cytoplasm	Krt5	IDA		Mouse	MGI:MGI:2662799|PMID:12657653
Cellular Component	GO:0005737	cytoplasm	Krt5	IDA		Mouse	MGI:MGI:6280798|PMID:29518391
Cellular Component	GO:0070062	extracellular exosome	KRT5	HDA		Human	PMID:19199708
Cellular Component	GO:0005882	intermediate filament	KRT5	IDA		Human	PMID:10852826
Cellular Component	GO:0045095	keratin filament	KRT5	IDA		Human	PMID:22705788
Cellular Component	GO:0045095	keratin filament	KRT5	IDA		Human	PMID:7679677
Cellular Component	GO:0045095	keratin filament	Krt5	IDA		Mouse	PMID:21464233
Cellular Component	GO:0045095	keratin filament	Krt5	IDA		Mouse	PMID:7679677
Cellular Component	GO:0045095	keratin filament	Krt5	IDA		Rat	PMID:14551252|RGD:1302413
Cellular Component	GO:0016020	membrane	KRT5	HDA		Human	PMID:19946888
Cellular Component	GO:0005634	nucleus	KRT5	HDA		Human	PMID:21630459
Cellular Component	GO:0005886	plasma membrane	Krt5	IDA		Mouse	PMID:21464233
Biological Process	GO:0031101	fin regeneration	krt5	IEP		Zfish	PMID:22278371
Biological Process	GO:0045107	intermediate filament polymerization	Krt5	IMP		Mouse	MGI:MGI:2179054|PMID:11408584
Biological Process	GO:0030334	regulation of cell migration	Krt5	IMP		Mouse	MGI:MGI:7260195|PMID:19267394
Biological Process	GO:0032880	regulation of protein localization	Krt5	IMP		Mouse	MGI:MGI:7260195|PMID:19267394
Biological Process	GO:0009612	response to mechanical stimulus	Krt5	IMP		Mouse	MGI:MGI:2179054|PMID:11408584

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern