Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes KRT4
  • Mouse genes Krt4
  • Rat genes Krt4
  • Zfish genes krt4,krt5
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Krt4

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	KRT4	IPI	UniProtKB:Q8E473	Human	PMID:17709412
Molecular Function	GO:0005515	protein binding	KRT4	IPI	UniProtKB:P14079	Human	PMID:22458338
Molecular Function	GO:0005515	protein binding	KRT4	IPI	UniProtKB:A1A4E9	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	KRT4	IPI	UniProtKB:O76015	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	KRT4	IPI	UniProtKB:P19012	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	KRT4	IPI	UniProtKB:Q14525	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	KRT4	IPI	UniProtKB:Q6A162	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	KRT4	IPI	UniProtKB:O76015	Human	PMID:29892012
Molecular Function	GO:0005515	protein binding	KRT4	IPI	UniProtKB:Q9BYV2	Human	PMID:31391242
Molecular Function	GO:0005515	protein binding	KRT4	IPI	UniProtKB:O76015	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	KRT4	IPI	UniProtKB:P13646	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	KRT4	IPI	UniProtKB:Q14525	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	KRT4	IPI	UniProtKB:Q6A162	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	KRT4	IPI	UniProtKB:O76013-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT4	IPI	UniProtKB:O76014	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT4	IPI	UniProtKB:O76015	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT4	IPI	UniProtKB:P08727	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT4	IPI	UniProtKB:P08779	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT4	IPI	UniProtKB:P13646	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT4	IPI	UniProtKB:P19012	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT4	IPI	UniProtKB:Q14525	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT4	IPI	UniProtKB:Q15323	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT4	IPI	UniProtKB:Q2M2I5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT4	IPI	UniProtKB:Q2TAC2-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT4	IPI	UniProtKB:Q6A162	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT4	IPI	UniProtKB:Q7Z3Y7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT4	IPI	UniProtKB:Q7Z3Y8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT4	IPI	UniProtKB:Q7Z3Z0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT4	IPI	UniProtKB:Q86XR8-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT4	IPI	UniProtKB:Q92764	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT4	IPI	UniProtKB:Q96KQ4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT4	IPI	UniProtKB:Q9BYV2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT4	IPI	UniProtKB:Q9NWQ9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT4	IPI	UniProtKB:Q9UGJ1-2	Human	PMID:32296183
Cellular Component	GO:0009986	cell surface	KRT4	IDA		Human	PMID:17709412
Cellular Component	GO:0045111	intermediate filament cytoskeleton	KRT4	IDA		Human	PMID:21371075
Cellular Component	GO:0045095	keratin filament	KRT4	IDA		Human	PMID:21371075
Cellular Component	GO:0005634	nucleus	KRT4	HDA		Human	PMID:21630459
Biological Process	GO:0007010	cytoskeleton organization	KRT4	IMP		Human	PMID:21371075
Biological Process	GO:0030855	epithelial cell differentiation	Krt4	IMP		Mouse	MGI:MGI:1278069|PMID:9727004
Biological Process	GO:0031101	fin regeneration	krt5	IEP		Zfish	PMID:22278371
Biological Process	GO:0050680	negative regulation of epithelial cell proliferation	Krt4	IMP		Mouse	MGI:MGI:1278069|PMID:9727004

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern