Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes KLRD1
  • Mouse genes Klrd1
  • Rat genes Klrd1
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Klrd1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0062082	HLA-E specific inhibitory MHC class Ib receptor activity	KLRD1	IDA		Human	PMID:9486650
Molecular Function	GO:0023024	MHC class I protein complex binding	KLRD1	IPI	UniProtKB:P13747	Human	PMID:18448674
Molecular Function	GO:0023030	MHC class Ib protein binding, via antigen binding groove	KLRD1	IPI	UniProtKB:P13747	Human	PMID:25631937
Molecular Function	GO:1990405	protein antigen binding	KLRD1	IDA		Human	PMID:18448674
Molecular Function	GO:0005515	protein binding	KLRD1	IPI	UniProtKB:P13747	Human	PMID:18083576
Molecular Function	GO:0005515	protein binding	KLRD1	IPI	UniProtKB:P26715	Human	PMID:18083576
Molecular Function	GO:0005515	protein binding	KLRD1	IPI	UniProtKB:P26717	Human	PMID:18083576
Molecular Function	GO:0005515	protein binding	KLRD1	IPI	UniProtKB:P26715	Human	PMID:18448674
Molecular Function	GO:0005515	protein binding	KLRD1	IPI	UniProtKB:P26717	Human	PMID:18448674
Molecular Function	GO:0005515	protein binding	KLRD1	IPI	UniProtKB:P26715	Human	PMID:32575403
Molecular Function	GO:0005515	protein binding	KLRD1	IPI	UniProtKB:P26717	Human	PMID:32575403
Molecular Function	GO:0005515	protein binding	KLRD1	IPI	UniProtKB:P01889	Human	PMID:8046333
Molecular Function	GO:0005515	protein binding	KLRD1	IPI	UniProtKB:P26717	Human	PMID:9655483
Cellular Component	GO:0009897	external side of plasma membrane	Klrd1	IDA		Mouse	PMID:14707119
Cellular Component	GO:0009897	external side of plasma membrane	Klrd1	IDA		Mouse	PMID:16973387
Cellular Component	GO:0005886	plasma membrane	KLRD1	IDA		Human	PMID:18448674
Cellular Component	GO:0005886	plasma membrane	KLRD1	IDA		Human	PMID:9485206
Cellular Component	GO:0005886	plasma membrane	KLRD1	IDA		Human	PMID:9486650
Cellular Component	GO:0005886	plasma membrane	KLRD1	IDA		Human	PMID:9655483
Cellular Component	GO:0043235	receptor complex	KLRD1	IPI		Human	PMID:18448674
Cellular Component	GO:0043235	receptor complex	KLRD1	IDA		Human	PMID:18448674
Biological Process	GO:0002228	natural killer cell mediated immunity	KLRD1	IDA		Human	PMID:18448674
Biological Process	GO:0045953	negative regulation of natural killer cell mediated cytotoxicity	KLRD1	IDA		Human	PMID:9486650
Biological Process	GO:0001915	negative regulation of T cell mediated cytotoxicity	KLRD1	IDA		Human	PMID:9485206
Biological Process	GO:0045954	positive regulation of natural killer cell mediated cytotoxicity	KLRD1	IDA		Human	PMID:9754572
Biological Process	GO:0002223	stimulatory C-type lectin receptor signaling pathway	KLRD1	IDA		Human	PMID:9655483

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern